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Clinical and Radiographic Evaluation of Indirect Pulp Capping in Primary and Permanent Teeth With Different Materials

Not Applicable
Completed
Conditions
Dental Pulp Capping
Interventions
Drug: Mineral Trioxide Aggregate
Drug: TheraCal LC
Registration Number
NCT03606681
Lead Sponsor
Altinbas University
Brief Summary

Indirect pulp capping (IPC) is a treatment that preserves pulp's vitality. Several materials have been used for this procedure. The aim of this study is to evaluate the radiographic and clinical outcomes of TheraCal LC (Bisco Inc., Schaumburg, IL, USA) and to compare it with mineral trioxide aggregate (MTA) (Pro Root MTA, Dentsply Tulsa, Johnson City, TN, USA) and calcium hydroxide \[Ca(OH)2\] (Dycal, Dentsply De Trey Konstanz, Germany) biomaterials in IPC treatment.

Detailed Description

A total of 295 teeth, including second primary molars and first permanent molars with IPC indications from healthy and cooperative children between the ages of 4-15, were included in this study. Teeth were divided into three groups according to the materials used for pulp capping. Indirect pulp treatment was applied using Dycal for 91 teeth, ProRoot MTA for 89 teeth and TheraCal LC for 115 teeth. Primary molars were restored with the compomer material, and permanent molars were restored with the resin composite material. Restorations were evaluated with the Modified United States Public Health Service (modified USPHS) criteria. Clinical and radiographic findings were evaluated for 24 months at follow-up.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
300
Inclusion Criteria
  • teeth with clinical and radiographical indications of indirect pulp capping
  • systemically healthy and cooperative children
Exclusion Criteria
  • teeth with contraindications of indirect pulp capping: Clinical Exclusion Criteria
  • Pain (spontaneous and chronic)
  • Fistula
  • Acute pulpal inflammation
  • Pain with percussion
  • Pathologic mobility
  • Abscess
  • Devitality symptoms (negative response to thermal pulp test) Radiographic Exclusion Criteria
  • Progression of caries lesion to pulp
  • Perforation of pulp
  • Intermittent or irregular lamina dura
  • Expanded range of periodontal ligament
  • Periapical radiolucency
  • Internal and external resorption
  • systemically unhealthy and uncooperative children

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Calcium Hydroxide (Dycal)Calcium HydroxideIndirect pulp capping treatment with Calcium Hydroxide
Mineral Trioxide Aggregate (ProRoot MTA)Calcium HydroxideIndirect pulp capping treatment with Mineral Trioxide Aggregate
Theracal LCCalcium HydroxideIndirect pulp capping treatment with Theracal LC
Calcium Hydroxide (Dycal)Mineral Trioxide AggregateIndirect pulp capping treatment with Calcium Hydroxide
Calcium Hydroxide (Dycal)TheraCal LCIndirect pulp capping treatment with Calcium Hydroxide
Mineral Trioxide Aggregate (ProRoot MTA)Mineral Trioxide AggregateIndirect pulp capping treatment with Mineral Trioxide Aggregate
Theracal LCMineral Trioxide AggregateIndirect pulp capping treatment with Theracal LC
Mineral Trioxide Aggregate (ProRoot MTA)TheraCal LCIndirect pulp capping treatment with Mineral Trioxide Aggregate
Theracal LCTheraCal LCIndirect pulp capping treatment with Theracal LC
Primary Outcome Measures
NameTimeMethod
Clinical success rates of the indirect pulp capping biomaterials24 months

No pathological symptom like abscess, fistulas or pain at percussion

Secondary Outcome Measures
NameTimeMethod
Success rates according to Modified USPHS criterias24 months

No failed restorations during the controls

Radiographical success rates of the indirect pulp capping biomaterials24 months

No radiolucency or root resorption, healing with dentin bridge

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