Analgesic Mechanisms of Percutaneous Electrolysis

Not Applicable

Completed

• Conditions: Percutaneous Electrolysis; Analgesia; Pain; Pain Modulation; Endogenous Analgesia System
• Interventions: Other: Sham intervention; Other: High intensity percutaneous electrolysis; Other: Low intensity percutaneous electrolysis

• Registration Number: NCT05097937
• Lead Sponsor: University of Salamanca

Brief Summary

Percutaneous electrolysis is based on the application of a galvanic current through an acupuncture needle. The underlying mechanisms that explain the efficacy of this technique are not completely well understood. The objective is to delve into the neurophysiological analgesic effects of percutaneous electrolysis. Participants will be assigned to one of three intervention groups. The analgesic effects of the technique will be evaluated by means of variables related to endogenous pain modulation.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-10-16
• Study First Submitted QC: 2021-10-16
• Study First Posted: 2021-10-28
• Study Start: 2021-11-22
• Status Verified: 2022-02
• Primary Completion: 2022-02-11
• Study Completion: 2022-02-11
• Last Update Submitted: 2022-02-14
• Last Update Posted: 2022-02-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 54

Inclusion Criteria

• Asymptomatic subjects
• Signature of the informed consent

Exclusion Criteria

• Fear of needles
• Any pathology or process that causes pain
• Neurological, rheumatologic, cardiovascular or metabolic diseases
• Cutaneous alterations and cognitive or sensitivity disorders
• Pregnancy
• Recent intake of alcohol or caffeine
• Vigorous physical activity on the day of testing

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Sham intervention	Sham intervention	The needle will be inserted for 90 seconds without galvanic current.
High intensity percutaneous electrolysis	High intensity percutaneous electrolysis	Participants will receive three impacts of galvanic current with an intensity of 3 mA for 3 seconds each.
Low intensity percutaneous electrolysis	Low intensity percutaneous electrolysis	Galvanic current will be applied with an intensity of 0.3 mA for 90 seconds.

Primary Outcome Measures

Name	Time	Method
Changes from baseline in Pressure Pain Thresholds (PPT)	Baseline and immediately after the intervention	PPTs will be measure by algometry in the common extensor tendon of the epicondyle, bicipital groove and tibialis anterior muscle (all of the right side).

Secondary Outcome Measures

Name	Time	Method
Changes from baseline in Temporal Summation (TS)	Baseline and immediately after the intervention	Assessed by Verbal Numeric Rating Scale (11-point). 10 consecutive pressures will be applied in the three previous locations (epicondyle, bicipital groove and tibialis anterior) with the algometer at the intensity of the pressure pain threshold
Changes from baseline in Conditioned Pain Modulation (CPM)	Baseline and immediately after the intervention	CPM will be assess by upper extremity submaximal effort tourniquet test with algometric measures in the common extensor tendon of the epicondyle, bicipital groove and tibialis anterior muscle (all of the right side).

Trial Locations

Locations (1)

Facultad de Enfermería y Fisioterapia de la Universidad de Salamanca; 🇪🇸 Salamanca, Spain