Degrading traumatic memories, a functional MRI study in PTSD
Completed
- Conditions
- posttraumatic stress disorder or anxiety disorderPTSD10002861
- Registration Number
- NL-OMON40084
- Lead Sponsor
- VUmc, Vakgroep Psychiatrie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
1. Adult with age between 18 and 65 years
2. Diagnosis of PTSD (DSM-IV)
3. Single or multiple separate traumatic events (type I trauma)
Exclusion Criteria
1. Repeated sexual and/or physical abuse (type II trauma)
2. Psychotic and substance-use disorders
3. Confounding medical conditions
4. Past month psychotropic/cardiovascular medication use.
5. Contra-indications for MRI scanning (metal inplants, pregnancy, claustrophobia)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Subjective vividness and emotionality of negative emotional memories and<br /><br>related neural activation (percentage BOLD<br /><br>signal change) during memory recall.</p><br>
- Secondary Outcome Measures
Name Time Method <p>cognitive functioning/working memory (n-back task)</p><br>