NCT04919356终止不适用
G2019S LRRK2 Parkinson's Disease: Increasing Awareness and Genetic Testing Program
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 836
- 试验地点
- 1
- 主要终点
- Identify Parkinson's patients with the G2019S mutation in their LRRK2 gene
研究概览
简要总结
Increase awareness of the G2019S LRRK2 mutation in Parkinson's and no cost genetic testing program.
详细描述
This program is intended to increase awareness of genetic Parkinson's, in particular the G2019S LRRK2 mutation, and provide no cost genetic testing to determine if they carry the G2019S LRRK2 mutation.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participant eligible for enrollment in the program must meet all of the following criteria:
- •Participant must be a person diagnosed with Parkinson's disease who is 18 years or older.
- •Participant is under the care of a physician for their Parkinson's disease.
- •Participant is able to read, write and understand English, and reside in a country where the shipment of biological samples is allowed.
- •Participant is able to grant informed consent.
- •In the case of participants, willing to participate in a free genetic testing program to determine if they carry the G2019S LRRK2 mutation.
- •Willing to be notified of eligibility for clinical studies (if appropriate).
- •Particpants who already believe they have tested positive for the mutation will be allowed to be retested through this program and be notified of potential eligibility for studies.
排除标准
- •Inability to meet any of the inclusion criteria.
- •Participant has received on of the following advanced treatments to manage their Parkinson's: gene therapy, deep brain stimulation (DBS), injections into the brain, continuous infusion of medication into their stomach/intestines with a pump.
结局指标
主要结局
Identify Parkinson's patients with the G2019S mutation in their LRRK2 gene
时间窗: 2 years
To identify Parkinson's patients with the G2019S mutation in their LRRK2 gene through whole exome sequencing in order to support the development of an oral precision medicine.
次要结局
- Understand the proportion of Parkinson's patients who have a G2019S LRRK2 mutation(2 years)
- Increase awareness of the importance of genetic testing in Parkinson's disease(2 years)
- Increase interest of healthcare providers and patients participation in clinical trials(2 years)
研究者
研究点 (1)
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