ESP Block in Radical Prostatectomy
- Conditions
- Erector Spinae Plane Block
- Interventions
- Procedure: ESP block
- Registration Number
- NCT05170373
- Lead Sponsor
- Istanbul Medeniyet University
- Brief Summary
Our study aimed to examine the effects of ultrasound guided erector spinae plane block in radical prostatectomy surgery on pain and surgical stress response, to reduce adrenocortical and sympathetic discharge due to anesthesia and surgery, and to reduce peroperative opioid analgesic consumption.
- Detailed Description
In this study 46 patients between the ages of 30-74, American Society of Anesthesiologists (ASA) score I-II and undergoing radical prostatectomy surgery at T.R. Ministry Of Health İstanbul Göztepe Prof. Dr. Süleyman Yalçın City Hospital were included. The patients were randomly divided into two groups as ESPB applied Group B (n=23) and not Group K (n=23). Patient-controlled analgesia (PCA) was initiated in all patients for postoperative analgesia. Patients' demographic data (age, gender, ASA score), intraoperative hemodynamic data, intraoperative and postoperative additional narcotic consumption, postoperative Numeric Rating Scale (NRS) scores (postoperative 0, 5 and 20 minutes and Then, 1, 3, 6, 12, 18 and 24 h), postoperative nausea-vomiting scores and possible complications related to block and / or surgery were recorded.Intraoperative MAP, HR, SpO2, BIS values of patients in both groups were recorded every 5 minutes. Blood glucose, insulin, cortisol, prolactin and C-reactive protein (CRP) were studied three times; preop morning at 6:00, intraoperative when surgical incision closing and postoperative 24h. in order to evaluate the surgical stress response in the patients.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 46
- ASA I-II
- diabetes
- coagulopathy
- local anesthetic
- drug allergy
- long hospitalization history,
- hormone disorder
- advanced organ failure
- history of steroid use
- vertebral anomalies
- mental retardation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description ESP group ESP block -
- Primary Outcome Measures
Name Time Method prolactin postoperative 24 hours. µg/L
cortisol postoperative 24 hours. µg/dL
Numeric Pain Scale postoperative 24 hours. Between 1-10. 1: no pain, 10: worst possible pain
insulin postoperative 24 hours. µIU/mL
C-reactive protein postoperative 24 hours. mg/L
Blood glucose postoperative 24 hours. mg /dL
- Secondary Outcome Measures
Name Time Method Remifentanil Consumption Speed 3 hours µg /kg/dk
Trial Locations
- Locations (1)
Istanbul Suleyman Yalcin City Hospital
🇹🇷Istanbul, Turkey