Effect of Daily Steps on Fat Metabolism

Not Applicable

Completed

• Conditions: Atherosclerosis; Metabolic Syndrome
• Interventions: Behavioral: Very Low Steps; Behavioral: Low Steps; Behavioral: Moderate Steps

• Registration Number: NCT03697382
• Lead Sponsor: University of Texas at Austin

Brief Summary

Reduced ambulatory activity has been shown to effect the response to a high fat tolerance test (HFTT) after acute exercise. This study will evaluate the effect of varying levels of daily ambulation on response to a HFTT after an acute aerobic exercise bout.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-09-25
• Study Start: 2018-09-29
• Study First Submitted QC: 2018-10-03
• Study First Posted: 2018-10-05
• Primary Completion: 2020-02-15
• Study Completion: 2020-05-31
• Status Verified: 2021-09
• Last Update Submitted: 2021-09-29
• Last Update Posted: 2021-09-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

Not provided

Exclusion Criteria

• Cardiovascular problems (e.g. pre-existing heart issues, coronary artery disease, hypertension, etc.)
• Respiratory problems
• Musculoskeletal problems that prevent prolonged sitting or exercise
• Obesity
• Susceptibility to fainting
• Pregnancy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Very Low Steps	Very Low Steps	Subjects will be asked to undergo reduced daily stepping to a level of 2,500 steps/d for 2 days. On the evening of day 2, they will be asked to run at 65% of VO2max for 1-hour.
Low Steps	Low Steps	Subjects will be asked to undergo reduced daily stepping to a level of 5,000 steps/d for 2 days. On the evening of day 2, they will be asked to run at 65% of VO2max for 1-hour.
Moderate Steps	Moderate Steps	Subjects will be asked to undergo reduced daily stepping to a level of 7,500 steps/d for 2 days. On the evening of day 2, they will be asked to run at 65% of VO2max for 1-hour.

Primary Outcome Measures

Name	Time	Method
6-Hour Plasma Triglyceride Area Under the Curve	6-hours	Areas under the curve for triglyceride concentration will be calculated for hourly samples from a 6-hour lipid tolerance test.

Secondary Outcome Measures

Name	Time	Method
6-Hour Plasma Insulin Area Under the Curve	6-hours	Areas under the curve for insulin concentration will be calculated for hourly samples from a 6-hour lipid tolerance test
6-Hour Plasma Glucose Area Under the Curve	6-hours	Areas under the curve for glucose concentration will be calculated for hourly samples from a 6-hour lipid tolerance test.

Trial Locations

Locations (1)

University of Texas at Austin Human Performance Laboratory; 🇺🇸 Austin, Texas, United States