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Clinical Trials/NCT00607815
NCT00607815
Completed
Not Applicable

A Comparison of CPT vs PCT for Veterans

VA Office of Research and Development1 site in 1 country79 target enrollmentJune 15, 2009
ConditionsPTSD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
PTSD
Sponsor
VA Office of Research and Development
Enrollment
79
Locations
1
Primary Endpoint
Clinician Administered PTSD Scale
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

The purpose of this study is to compare the effectiveness of Cognitive Processing Therapy (CPT) versus Present Centered Therapy (PCT) for male OEF/OIF Veterans with combat related PTSD.

Detailed Description

The purpose of this study is to compare the effectiveness of Cognitive Processing Therapy (CPT) versus Present Centered Therapy (PCT) for male OEF/OIF Veterans with combat related PTSD. CPT has been shown to be effective in treating trauma survivors in several treatment outcome studies, but utility with Veterans has only been examined with male Veterans in one small pilot study. In addition CPT has never been compared to a treatment as usual or supportive psychotherapy condition to control for the specific and nonspecific elements of treatment. Although Cognitive Processing Therapy is one of the main treatment modalities at several VA's, including Cincinnati, it has never been compared to PCT, nor has it been used in a large, randomized study of male OEF/OIF Veterans. It is hypothesized that individual receiving CPT will show a larger reduction in posttraumatic stress disorder and related symptoms than those individuals receiving PCT. All male OEF/OIF Veterans will be screened for their appropriateness for the study by phone screen and then by an assessment technician. The Veteran will be assessed at pre, post, 3-month, and 1-year follow-up. The assessment technicians will be blind to the participant's condition. CPT is a 12 week long individual psychotherapy treatment shown to be effective at reducing PTSD and related symptoms for survivors of various types of traumas, including combat. PCT is a supportive counseling treatment that has been utilized as an alternative to waitlist control in VA cooperative studies of PTSD.

Registry
clinicaltrials.gov
Start Date
June 15, 2009
End Date
December 27, 2015
Last Updated
7 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • memory of the trauma;
  • able to read/write;
  • must be stable on medication for 3 months

Exclusion Criteria

  • Psychosis;
  • suicidal/homicidal intent;
  • alcohol/substance dependence;
  • no memory of the trauma

Outcomes

Primary Outcomes

Clinician Administered PTSD Scale

Time Frame: Post-treatment, at 3 months and 1 year

Clinician-rated PTSD symptom severity; higher is worse; range at post-treatment is 0 to 80; scale scores are summed.

PTSD Checklist (PCL)

Time Frame: post-treatment, at 3 months and 1 year

17-item patient self-reported PTSD severity; higher is worse; range at post-treatment is 17-73; scale scores are summed

Secondary Outcomes

  • Beck Depression Inventory - II (BDI-II)(post-treatment, at 3 months and 1 year)
  • State-Trait Anger Scale (STAXI)(post-treatment, at 3 months and 1 year)
  • State-Trait Anxiety Scale(post-treatment, at 3 months and 1 year)

Study Sites (1)

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