Manganese in Women With Encephalopathy
- Conditions
- Hepatic Encephalopathy
- Registration Number
- NCT00985010
- Lead Sponsor
- Materno-Perinatal Hospital of the State of Mexico
- Brief Summary
Objective:
Report manganese serum levels and mortality in encephalopathic patients.
Patients and participants:
Consecutive patients aged \> 18 years, with hepatic encephalopathy and informed consent signed by their families.
Interventions:
Patients' clinical characteristics as well as biochemical tests of renal function, hemoglobin, glucose and albumin levels were obtained as well as a blood sample to analyze manganese levels with a graphite furnace atomic absorption spectrometer.
Hypothesis:
There is a difference in the manganese levels between male and female patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- TERMINATED
- Sex
- All
- Target Recruitment
- 9
- Consecutive patients aged > 18 years
- With hepatic encephalopathy
- Informed consent signed by their families
- Portal bypass surgery
- Cancer of any localization
- Known malignancy and other severe diseases which shorten life expectancy < 6 months
- Psychiatric illness
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Clinical Evolution six months Number of participants who died versus those who remained alive after 6 months of follow up since the first entrance at the Emergency Room
- Secondary Outcome Measures
Name Time Method Manganese Levels Up to six months we followed the recruited patients to determine who were still alive From encephalopathic patients, we took individual blood samples, analyzed in the biochemistry laboratory at the National Institute of Neurology and Neurosurgery, Mexico, City, with a graphite furnace atomic absorption spectrometer, according to the technique reported by Pleban.
Trial Locations
- Locations (1)
General Hospital "Dr. Darío Fernández Fierro"
🇲🇽Mexico, D.f., Mexico