Effects of Endurance Training on Patients With Reduced Left Ventricular Ejection Fraction (LVEF) and Cardiac Resynchronisation Therapy Especially for Cardiac Arrhythmias

Not Applicable

• Conditions: Heart Failure; Cardiac Resynchronisation Therapy; Sudden Cardiac Death
• Interventions: Behavioral: exercise training; Behavioral: endurance training

• Registration Number: NCT00472238
• Lead Sponsor: Charite University, Berlin, Germany

Brief Summary

A severely reduced left ventricular ejection fraction is associated with increased mortality due to pump failure as well as to malignant ventricular arrhythmia. We hypothesize that targeted training may lead to improved survival and to increased parameters of risk stratification for malignant arrhythmia. Additionally, the training may lead to an improved psychological and mental condition of the patients

Detailed Description

Not available

Study Timeline

• Status Verified: 2007-05
• Study First Submitted: 2007-05-10
• Study First Submitted QC: 2007-05-10
• Study First Posted: 2007-05-11
• Study Start: 2007-08
• Last Update Submitted: 2008-11-19
• Last Update Posted: 2008-11-20
• Study Completion: 2008-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• CRT Device

Exclusion Criteria

• refused informed consent

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1, Training	exercise training	Group for training therapy
2, Control	endurance training	-

Primary Outcome Measures

Name	Time	Method
aerobic threshold	3 months
left ventricular function	3 months

Secondary Outcome Measures

Name	Time	Method
quality of life	3 months

Trial Locations

Locations (1)

Charité campus Benjamin Franklin; 🇩🇪 Berlin, Germany