Effect of exercise training on left ventricular remodeling in diabetic patients with diastolic dysfunction: a pilot study
Not Applicable
Completed
- Conditions
- DiabetesMetabolic and Endocrine - Diabetes
- Registration Number
- ACTRN12610000943044
- Lead Sponsor
- Prof David L Hare
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Type 2 Diabetic patients with LV diastolic dysfunction as evidenced on echocardiography by a)Deceleration time > 220 msec and/or E’: < 8 cm/s, b) E/E'>10 who are suitable for exercise training intervention
Exclusion Criteria
1) Known coronary artery disease or evidence of ischaemia on baseline stress echocardiography.
2) Left ventricular ejection fraction < 45%
3) Significant (moderate or severe) valvular disease
4) Unstable heart failure needing > 2 medication changes in last 3 months
5) Unstable diabetes as evidenced by a) Hypoglycaemic events > 1/week, or b)HbA1c = 9.0%
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method