Effects of Exercise Therapy on Ventricular and Endothelial Function in Patients After Coronary Artery Bypass Surgery

Completed

• Conditions: Diabetes Mellitus, Type 2
• Interventions: Other: exercise capacity test

• Registration Number: NCT01990638
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

The purpose of this study was (1) to compare the peak exercise capacity and left ventricular diastolic function between patients with and without diabetes and (2) to investigate the interrelation among peak oxygen consumption, left ventricular diastolic function, blood sugar, and lipid profile.

Detailed Description

Not available

Study Timeline

• Study Start: 2004-11
• Primary Completion: 2005-04
• Study Completion: 2005-05
• Status Verified: 2013-11
• Study First Submitted: 2013-11-15
• Study First Submitted QC: 2013-11-15
• Last Update Submitted: 2013-11-15
• Study First Posted: 2013-11-21
• Last Update Posted: 2013-11-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 51

Inclusion Criteria

• well-controlled diabetes
• no history of myocardial infarction
• stable post coronary artery bypass surgery for at least 3 months

Exclusion Criteria

• heart failure,
• valvular disease,
• abnormal kidney or liver function,
• cerebrovascular disease,
• primary pulmonary disease,
• other systemic or acute illness that may impede the testing or training

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
DM group	exercise capacity test	-
non-DM group	exercise capacity test	-

Primary Outcome Measures

Name	Time	Method
left ventricular diastolic function	1 week	echocardiographic parameters

Secondary Outcome Measures

Name	Time	Method
flow-mediated dilation	1 week	flow-mediated dilation on right brachial artery
exercise capacity	1 week	oxygen consumption

Trial Locations

Locations (1)

National Taiwan University Hospital; 🇨🇳 Taipei, Taiwan