Ultrastructural Changes of Trabeculectomy Specimens in Patients With Uveitic Secondary Glaucoma
Completed
- Conditions
- Secondary GlaucomaUveitis
- Registration Number
- NCT00917670
- Lead Sponsor
- St. Franziskus Hospital
- Brief Summary
Ultrastructural analysis of trabeculectomy specimens of patients with uveitic secondary glaucoma.
To evaluate morphological changes and to compare to primary open angle glaucoma patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 10
Inclusion Criteria
- secondary uveitic glaucoma
- IOP > 24 mmhg with topical and/or systemic therapy
- need for surgical intervention to control IOP
Exclusion Criteria
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method morphological changes after surgery
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What ultrastructural changes in trabeculectomy specimens are associated with uveitic secondary glaucoma compared to primary open-angle glaucoma?
How do inflammatory markers in uveitic glaucoma patients correlate with structural alterations observed in trabeculectomy tissues?
What are the key molecular pathways affected in uveitic secondary glaucoma based on electron microscopy findings from trabeculectomy specimens?
Are there specific histopathological features in uveitic glaucoma trabeculectomy samples that differentiate them from primary glaucoma cases?
What therapeutic strategies targeting inflamed trabecular meshwork could be informed by ultrastructural analysis of uveitic secondary glaucoma specimens?
Trial Locations
- Locations (1)
Department of Anatomy II at University of Erlangen, Germany
🇩🇪Erlangen, Germany
Department of Anatomy II at University of Erlangen, Germany🇩🇪Erlangen, Germany