The effect of herbal product from Berberis integerrima on Non-Alcoholic Fatty Liver Disease

Phase 3

Recruiting

• Conditions: Fatty liver.; Fatty (change of) liver, not elsewhere classified; K76.0

• Registration Number: IRCT20210524051376N1
• Lead Sponsor: Babol University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 12 July 2021

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Increased liver echogenicity (grade 2 non-alcoholic fatty liver) based on ultrasonographic findings

Exclusion Criteria

The underlying illness (Diabetes mellitus, cardiovascular diseases, liver disease (cirrhosis, alcoholic liver disease, viral hepatitis, autoimmune hepatitis, primary biliary cirrhosis, biliary obstruction, hepatic damage induced by hereditary hemochromatosis drugs, sclerosis cholangitis and a deficiency of an antitrypsin), other serious diseases such as cancer; kidney failure and celiac disease
Pregnancy
Lactation
Drug history with increase hepatic steatosis risk (Tamoxifen, valproate sodium, ...
Antihyperlipidemic drugs
Malnutrition
special diets such as vegetarianism and raw eating
Alcohol consumption
Smoking and addiction
Acute psychiatric disorder

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The ultrasound image echogenicity of patients with Non-Alcoholic Fatty Liver Disease. Timepoint: 3 months after the start of the intervention. Method of measurement: Ultrasonography grading and lab test (TG, LDL,HDL, AST ,ALT).

Secondary Outcome Measures

Name	Time	Method
Body wheight. Timepoint: 3 months after the start of the intervention. Method of measurement: Measure weight (kg).