Investigating the effects of berberis vulgaris L. on the treatment of opiate withdrawal syndrome
Phase 2
- Conditions
- Patients addicted to opioids treated with methadone.Mental and behavioural disorders due to use of opioids
- Registration Number
- IRCT20180114038356N3
- Lead Sponsor
- Kerman University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 28
Inclusion Criteria
Opioid addiction of at least 2.3 grams per day continuously for at least one year,
Age between 20-60 years old
No history of medical comorbidities
No history of allergies to this plant
Exclusion Criteria
History of medical comorbidities
History of allergies to this plant
Do not take the capsules
Dissatisfaction with methadone dose reduction
Intolerance to some of side effects of the extract, such as dry mouth
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Examination of opioid withdrawal symptoms and neurological complications with the questionnaires. Timepoint: Before intervention and 7, 14 and 28 days after intervention. Method of measurement: Questionnaires.
- Secondary Outcome Measures
Name Time Method Assessment of depression, anxiety, sleep quality. Timepoint: Before intervention and 7, 14 and 28 days after intervention. Method of measurement: Questionnaires.