Effect of powdered Berberis vulgaris on vascular functio
Not Applicable
Recruiting
- Conditions
- hypertension.Essential (primary) hypertension
- Registration Number
- IRCT20160702028742N8
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 76
Inclusion Criteria
Willingness to participate in the study
Age between 20-65 years
Having elevated blood pressure (129/ < 85) or known hypertensive patients on medical treatment
At least one other classical cardiovascular disease risk factors, including hyperlipidemia or diabetes mellitus
Exclusion Criteria
BMI> 30
Patients on nitrate drugs
High doses of statins consumption (Atorvastatin>40 mg/day or Rosuvastatin>20 mg/day)
Regular consumption (more than once in a week) of vitamins or minerals supplements during past month
Chronic kidney disease stage 4 or 5
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Flow mediated dilation (FMD). Timepoint: Baseline and the end of the study. Method of measurement: sonography.
- Secondary Outcome Measures
Name Time Method Plasma ICAM-1. Timepoint: Baseline and the end of the study. Method of measurement: ELISA.;Plasma VCAM-1. Timepoint: Baseline and the end of the study. Method of measurement: ELISA.