The effect of Berberis Vulgaris extract, on Cutaneous Leishmaniasis
Phase 3
- Conditions
- Cutaneous Leishmaniasis.Cutaneous Leishmaniasis
- Registration Number
- IRCT2015060122512N1
- Lead Sponsor
- Mashhad University of Medical Sciences, Vice Chancellor for Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Presence of cutaneous leishmaniasis with less than 6 months of clinical course; Not receive any treatment 3 months before; Age 8 years and above; Lesion diameter less than 3 cm; The number of lesion less than 5; The lesion on the limbs and trunk with the exception of joints’ surface.
Exclusion criteria: Pregnancy; Lactating; Receiving simultaneous treatment with other methods during treatment course; History of significance renal, Pulmonary and cardiovascular disease; Create a secondary infection of the wound; Deterioration of the condition of the patient during the study; Immune suppressor drugs consumption; Do not run commands therapy.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method esion size change. Timepoint: Weekly until 8 weeks. Method of measurement: Measuring the size of induration and ulcer by caliper.
- Secondary Outcome Measures
Name Time Method Side effects: erythema, itching. Timepoint: Weekly. Method of measurement: Clinical evaluation.