Skip to main content
Clinical Trials/NCT06998576
NCT06998576RecruitingNot Applicable

Different Strokes for Different Folks - Leveraging on Social Networks for Public Health Education on Antibiotic Use and Antimicrobial Resistance

Tan Tock Seng Hospital1 site in 1 country3,300 target enrollmentStarted: July 21, 2025Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Recruiting
Sponsor
Enrollment
3,300
Locations
1
Primary Endpoint
Knowledge of antibiotic use - 3 questions from the World Health Organization's Antibiotic Resistance Multi-country Public Awareness Survey questionnaire

Study Overview

Brief Summary

This study aims to compare the effectiveness of health education facilitated by neighborhood food and beauty establishments with that facilitated by clinics in increasing the public's knowledge of antibiotic use and antimicrobial resistance (AMR) and improving antibiotic behaviors.

The quasi-experimental study will involve a total of 3300 patrons of the 10 most popular consenting clinics, food and beauty establishments respectively, in two neighborhoods in Singapore.

Recruitment Process

  1. Participants will scan the QR code on the posters in the participating clinics/establishments
  2. Read the study information sheet
  3. Consent will be implied on submission of survey
  4. Total recruitment period: One year
  5. Target: 3300 patrons of the 30 establishments (10 each of clinics, food, and beauty establishments)

Intervention Structure

  1. Participants will complete a pre-intervention/baseline survey (#1)
  2. Intervention includes an animated educational video with key messages on appropriate antibiotic use and AMR
  3. Followed by immediate post-intervention survey (#2)
  4. Provide contact details (mobile phone number) for reimbursement & future follow-up online surveys
  5. Complete follow-up online surveys: at 1 month post-intervention (#3), 3 months post-intervention (#4) and 6 months post-intervention (#5)

Expected Outcomes Increase in public knowledge of antibiotic use and AMR, and antibiotic behaviors through health education facilitated by neighborhood food and beauty establishments, in addition to that facilitated by clinics

Detailed Description

According to the World Health Organisation (WHO), antimicrobial resistance (AMR) is one of top 10 global public health threats facing humanity [1,2] and is primarily driven by overuse and misuse of antibiotics [3]. Majority of the population-based national AMR educational campaigns focused on raising public awareness of appropriate antibiotic use and promoting action against antimicrobial resistance have shown mixed results largely due to its "one-size-fits-all" approach [4,5,6].

While healthcare providers are key players in health communication and considered most trusted sources of health information across all age groups [7], there is a need to identify and harness non-healthcare related establishments which can serve as trusted sources of health information especially for younger age groups who are less likely to have healthcare encounters [8-10]. The present study aims to engage non-healthcare establishments (food and beauty) with high degree centrality in the community identified through social network analysis, and evaluate the effectiveness of sharing health information about antibiotic use facilitated by non-healthcare establishments (food and beauty) as compared to traditional healthcare sources (clinics).

The Investigators conducted an exploratory sequential mixed methods study to identify both healthcare and non-healthcare (food and beauty) establishments which were highly frequented by the residents in the community. Findings from the above study were used to select the top 10 highly frequented healthcare and non-healthcare (food and beauty) establishments.

A quasi-experimental study will be conducted to compare the effectiveness of sharing health information about antibiotic use and AMR facilitated through healthcare clinics, and beauty and food establishments in 2 neighborhoods. Participants (patients/patrons) who visit the participating establishments (clinics/food establishments/beauty establishments) will be invited to take part in the study by scanning the QR code on the recruitment posters placed inside the premises. Upon scanning the QR code, participants will proceed to complete a pre-intervention questionnaire survey (#1) on an online platform after going through the study information sheet. Upon completion of the survey #1, participants will be guided through embedded instructions to click on a link to access the health educational intervention. The educational intervention includes a short 2-minute animated video (developed based on the preferences of the community as identified from the results of the quantitative survey) will be hosted on a multimedia online platform providing key information on appropriate antibiotic use and AMR. After viewing the video, the participants will be subsequently led to the post-intervention survey #2 via a link. Before submitting survey #2, contact details (mobile number) and the preferred payment method will be collected for reimbursement purposes and future follow-up surveys. The enrolled participants will be re-contacted by the study team via a mobile messaging service (such as WhatsApp), and will be guided through embedded instructions to complete three more surveys (#3, #4 & #5) at 1-, 3-, and 6-month post-intervention to assess knowledge on antibiotic use and AMR and behaviors on antibiotic use. Participants will be recruited from all 30 participating establishments (10 clinics, 10 F&B shops, 10 beauty salons) for the entire study duration of one year and will be followed up for 6 months after the intervention.

Study Design

Study Type
Interventional
Allocation
Non Randomized
Intervention Model
Parallel
Primary Purpose
Other
Masking
None

Eligibility Criteria

Ages
21 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •Adults aged 21 years and above
  • •Patrons of the 30 participating healthcare clinics, food and beauty establishments

Exclusion Criteria

  • •Patrons who are already enrolled in the study at one of the 30 participating establishments

Arms & Interventions

Healthcare clinics

Experimental

Ten healthcare clinics will be chosen. Patients will enrol into the study by scanning the QR code on the recruitment poster at the participating healthcare clinics will access the health educational intervention.

Intervention: Animated educational video on antibiotic use (Behavioral)

Food establishments

Experimental

Ten food establishments will be chosen. Patrons will enrol in the study by scanning the QR code on the recruitment poster at the participating F&B shops will access the health educational intervention.

Intervention: Animated educational video on antibiotic use (Behavioral)

Beauty establishments

Experimental

Ten beauty etablishments will be chosen. Patrons will enrol in the study by scanning the QR code on the recruitment poster at the participating beauty establishments will access the health educational intervention.

Intervention: Animated educational video on antibiotic use (Behavioral)

Outcomes

Primary Outcomes

Knowledge of antibiotic use - 3 questions from the World Health Organization's Antibiotic Resistance Multi-country Public Awareness Survey questionnaire

Time Frame: The participants will be followed up for 6 months following the intervention.

Proportion of participants with good knowledge of antibiotic use at baseline (pre-intervention), immediate post-intervention, and at 1-month, 3-month and 6-month post-intervention.

Knowledge of AMR - 8 questions from the World Health Organization's Antibiotic Resistance Multi-country Public Awareness Survey questionnaire

Time Frame: The participants will be followed up for 6 months following the intervention.

Proportion of participants with good knowledge of AMR at baseline (pre-intervention), immediate post-intervention, and at 1-month, 3-month and 6-month post-intervention.

Appropriate antibiotic use - 6 questions adapted from the US Centers for Disease Control and Prevention's advisory on appropriate antibiotic use

Time Frame: The participants will be followed up for 6 months following the intervention.

Proportion of participants who use antibiotics appropriately at baseline (pre-intervention), immediate post-intervention, and at 1-month, 3-month and 6-month post-intervention.

Secondary Outcomes

  • Reach - using the RE-AIM framework(one year study duration for enrollment)
  • Implementation fidelity - using the RE-AIM framework(one year study duration for doing fidelity checks)

Investigators

Sponsor
Tan Tock Seng Hospital
Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Chow Li Ping Angela

Senior Consultant, Department of Epidemiology and Preventive Medicine

Tan Tock Seng Hospital

Study Sites (1)

Loading locations...

Similar Trials