evaluation of insulin resistance before and after levothyroxine replacement in subclinical hypothyroidism patients
- Conditions
- insulin resistance in patients with subclinical hypothyroidism
- Registration Number
- TCTR20210317001
- Lead Sponsor
- alazhar university hospital at new deiitta
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending (Not yet recruiting)
- Sex
- Female
- Target Recruitment
- 32
Inclusion Criteria
female patient age more than 18 years old, TSH level more than 5 mIU/l, free T4 and free T3 concentrations within the normal range
Exclusion Criteria
DM, Other endocrine diseases
Drugs example(Insulin sensitizers, Contraceptive pills, Corticosteroid).
Pregnancy.
Sever co morbid diseases.as renal. liver and heart failure
Patient aready on thyroxine treatment
Patient with chronic HCV
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method normalization of TSH 3 months after end of intervention TSH by laboratory investigation
- Secondary Outcome Measures
Name Time Method normalization of insulin resistance 3 months after end of intervention HOMA IR by laboratory investigation