Comparative study of dexmedetomidine-fentanyl vs. midazolam-ketamine in sedation in children undergoing bone marrow biopsy
Phase 3
Recruiting
- Conditions
- .
- Registration Number
- IRCT20160301026866N11
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 70
Inclusion Criteria
Children 2 to 6 years of age
ASA I and ASA II classes
, bone marrow biopsy candidates
Exclusion Criteria
Congenital heart and respiratory disease
productive cough
fever
wheezing or cracking in the lungs
parental withdrawal from the project
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Sedation Score. Timepoint: Immediately before prescribing the drug, 2,5,10,15 minutes after drug administration. Method of measurement: Ramsay Scale.;Mean Arterial Blood pressure. Timepoint: Immediately before prescribing the drug, 2, 5 ,10,15 minutes after drug administration. Method of measurement: Anesthesia monitoring device.;Heart Rate. Timepoint: Immediately before prescribing the drug, 2, 5,10,15 minutes after drug administration. Method of measurement: Anesthesia monitoring device.
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What are the molecular mechanisms of dexmedetomidine-fentanyl in pediatric sedation for bone marrow biopsy?
How does the efficacy of dexmedetomidine-fentanyl compare to midazolam-ketamine in children undergoing bone marrow biopsy?
Are there specific biomarkers that predict response to dexmedetomidine-fentanyl in pediatric sedation for bone marrow biopsy?
What are the potential adverse events associated with midazolam-ketamine sedation in children undergoing bone marrow biopsy?
What are the current standard-of-care sedation protocols for pediatric bone marrow biopsy compared to IRCT20160301026866N11 trial interventions?