Pharmacodynamic model of effect-site concentration of propofol for loss of consciousness in the patients done chemotherapy.
- Conditions
- Neoplasms
- Registration Number
- KCT0003769
- Lead Sponsor
- Inje University Busan Paik Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
experimental group(C): Patients undergoing colorectal cancer surgery or intestinal reconstruction under general anesthesia, Patients with a history of chemotherapy within 12 months before surgery, aged 18 to 75 years, BMI 18-29 kg/m2, and American Society of. Anesthesiologists(ASA) physical status1, 2.
- control group(N): Patients undergoing colorectal cancer surgery or intestinal reconstruction under general anesthesia, Patients without a history of chemotherapy before surgery, aged 18 to 75 years, BMI 18-29 kg/m2, and American Society of. Anesthesiologists(ASA) physical status1, 2.
Patients with neurological, neuropsychiatric history, taking sadatives, taking chronic alcohol, who is expected to be difficult to maintain airway, difficult to communicate, or with a history of chomotherapy before the surgery 13 months prior to surgery.
Study & Design
- Study Type
- Observational Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Median effective effect-site concentration of propofol causing loss of consciousness
- Secondary Outcome Measures
Name Time Method Modified observer’s assessment of alertness/sedation scale