Cases With Traumatic and Non Traumatic Brain Damage Treated in the Intensive Care

Completed

• Conditions: Brain Injuries
• Interventions: Other: type of the brain injury

• Registration Number: NCT02475226
• Lead Sponsor: Umraniye Education and Research Hospital

Brief Summary

Cases of traumatic and nontraumatic brain damage have high rates of morbidity and mortality. In this study of cases being treated in the ICU for a diagnosis of brain damage, it was aimed to evaluate the relationship between mortality and the distribution of reason for and resulting type of brain damage and to determine other factors affecting mortality.

Detailed Description

After local ethics committee approval, a total of 1004 patients treated in the ICU in a 2-year period were retrospectively reviewed. 135 patients, determined with traumatic or nontraumatic brain damage, with a more than 24-hour stay in the ICU, included the study. Reasons for brain damage were determined as brain damage associated with pure head trauma (Group HT), head trauma accompanying general body trauma (Group HT+GBT) and spontaneous haemorrhage (Group SH). The type of brain damage was defined from the radiological diagnosis as subarachnoid haemorrhage, intracranial haemorrhage (ICH), subdural haematoma(SDH), epidural haematoma(EDH), skull fracture, brain contusion or a combination of these (COM).

Study Timeline

• Study Start: 2015-04
• Primary Completion: 2015-05
• Study Completion: 2015-05
• Status Verified: 2015-06
• Study First Submitted: 2015-06-15
• Study First Submitted QC: 2015-06-17
• Last Update Submitted: 2015-06-17
• Study First Posted: 2015-06-18
• Last Update Posted: 2015-06-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 135

Inclusion Criteria

• Patients treated in the ICU with the diagnose of traumatic or nontraumatic brain damage, with a more than 24-hour stay.

Exclusion Criteria

• Patients admitted less than 24 hour.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients with pure head trauma	type of the brain injury	type of the brain injury in patients with brain damage associated pure head trauma
Patients with body and head trauma	type of the brain injury	type of the brain injury in patients with brain damage associated both general body and head trauma
Patients with spontaneous hemorrhage	type of the brain injury	type of the brain injury in Patients with brain damage associated spontaneous hemorrhage

Primary Outcome Measures

Name	Time	Method
number of patients by brain damage types	2 years	distribution of the patients with brain damage over the brain damage reasons

Secondary Outcome Measures

Name	Time	Method
Number of factors effecting the mortality	2 years	duration time of intubation, duration time in the ICU, APACHE scores, GCS scores.

Trial Locations

Locations (1)

Istanbul Umraniye Education and Research Hospital; 🇹🇷 Istanbul, Turkey