Evaluation of Factors That Cause Secondary Brain Damage on Mortality and Morbidity in Patients Undergoing Emergency Surgery Due to Head Trauma.

Completed

• Conditions: Brain Injuries
• Interventions: Other: factors evaluation

• Registration Number: NCT04555772
• Lead Sponsor: Turkish Society of Anesthesiology and Reanimation

Brief Summary

Traumatic brain injury is combination damage that occurs as a result of a chain reaction of various metabolic events that develop after primary damage caused by trauma. Pathological events such as lactic acidosis, electrolyte imbalance, increased inflammation that occur during traumatic brain injury leads to poor prognosis in patients.

The retrospective study was conducted to investigate the effect of factors that may cause secondary damage, especially electrolyte imbalance and blood glucose levels, on mortality and morbidity in patients undergoing emergency surgery due to head trauma.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-11
• Primary Completion: 2019-01-11
• Study Completion: 2019-01-30
• Study First Submitted: 2020-07-29
• Status Verified: 2020-09
• Study First Submitted QC: 2020-09-14
• Last Update Submitted: 2020-09-14
• Study First Posted: 2020-09-21
• Last Update Posted: 2020-09-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 108

Inclusion Criteria

• patients who admitted to Bursa Uludag University hospital between 2013 and 2018
• patients diagnosed with traumatic brain injury and operated within the first 24 hours after admission

Exclusion Criteria

• pediatric patients
• patients that operated after 24 hour of admission

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Exitus Group	factors evaluation	Patients who did not respond to the treatments and lost their lives within 28 days of admission.
Healthy Group	factors evaluation	Patients who had been treated and recovered physically and gained cognitive functions completely.
Sequel Group	factors evaluation	Patients who could not gain their physical and cognitive functions.

Primary Outcome Measures

Name	Time	Method
mortality and morbidity in patients who underwent emergency operation within 24 hours after traumatic brain injury	5 years	It seems that secondary damage caused by metabolic events like eletrolyte imbalance in patients with head trauma should always keep in mind. If they encounter these situations, they should treat the patient and do replacements immediately.

Trial Locations

Locations (1)

Bursa uludag university; 🇹🇷 Bursa, Turkey