NCT05735405招募中不适用
Priming Effects of Aerobic Exercise on Cognitive Training of Patients With Ischemic and Hemorrhagic Stroke
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Neuropsychological test scores
研究概览
简要总结
The goal of this clinical trial is to test the effects of aerobic exercise and BDNF on patients with ischemic and hemorrhagic stroke during a computerized cognitive training.
The main questions it aims to answer are:
- Does a moderate intensity aerobic exercise, prior to a cognitive training, allow a better performance?
- Is it possible to exploit the timing of rehabilitation interventions to obtain greater effects? Participants will be divided in 2 groups. The experimental group will first perform 20 minutes of pedaling as a moderate intensity aerobic exercise. It will then participate in one-hour cognitive training sessions, with the aim of training attentional, working memory and executive functions. The control group will carry out the same interventions but in reverse order.
The researchers will compare the results of the cognitive training in the two groups to verify if the order of the interventions influences the results themselves.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients with a clinical diagnosis of stroke, both ischemic and haemorrhagic.
- •Patients admitted to the Specialist Rehabilitation Unit 1 of the "E. Spalenza - Don Gnocchi "of Rovato.
- •Overall score in the MoCA test ³ 26
- •In case of a diagnosis of aphasia, a test of verbal comprehension ("Token Test") with score in the norm, P.E. > 1
- •Hypertonic and spasticity picture compatible with the performance of motor activity of pedaling expected in the EA session.
- •Tolerance of physical exercise
- •Incoming electrocardiogram normal and free of anomalies
排除标准
- •Overall score in the MoCA test <26
- •In case of a diagnosis of aphasia, a test of verbal comprehension ("Token Test") with pathological or borderline score, P.E. £
- •Documented diagnosis of neurodegenerative diseases with impact on performance cognitive.
- •Severe acquired brain injury
- •Illiteracy
- •Status of hypertonus and spasticity not compatible with the performance of motor training
- •Excessive fatigue: the patient does not tolerate moderate intensity physical activity and accuses excessive fatigue during the preliminary test
- •Electrocardiogram at entrance with anomalies and / or altered
- •Ischemic heart disease
- •Cardiac disorders that are contraindications for aerobic activity of moderate intensity
结局指标
主要结局
Neuropsychological test scores
时间窗: Change in the neuropsychological test scores at 1 month
The experimental hypothesis is to obtain better scores in the experimental group on the neuropsychological tests used. T-tests and delta scores will be used to determine the quantitative change in the score.
次要结局
- Number of errors committed in the cognitive exercises(One month)
研究者
研究点 (2)
Loading locations...
相似试验
Unknown
不适用
A Study of Aerobic Exercise for Patients With Bipolar DisorderCognitive SymptomBipolar DisorderNCT03353337Guangzhou Psychiatric Hospital210
已完成
不适用
Combined Effects of Aerobic Exercise and Cognitive Training on Cognition After StrokeStrokeNCT01674790Marilyn MacKay-Lyons22
已完成
不适用
Effects of Aerobic Exercise on Cognition, Mood and Fatigue Following TBITraumatic Brain InjuryNCT00619463Icahn School of Medicine at Mount Sinai154
已完成
不适用
Cognitive Benefits of Aerobic Exercise Across the Age SpanCognitive FunctionNCT01179958New York State Psychiatric Institute305
尚未招募
不适用
Combined Aerobic Exercise and Cognitive Training in Seniors With Genetic Susceptibility for Alzheimer's DiseaseAlzheimer DiseaseNCT05163067Xuanwu Hospital, Beijing200