To Observe the Benefit of Adding Brachytherapy After CCRT on Resectable Esophageal Cancer Patients Without Surgery

Not Applicable

Recruiting

• Conditions: Esophageal Cancer

• Registration Number: NCT05145647
• Lead Sponsor: Chang Gung Memorial Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-9-3
• Last Update Posted: 2 September 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 18

Inclusion Criteria

Inclusion Criteria:<br><br> 1. Age of 20-85 years, with ECOG performance 0-2<br><br> 2. Thoracic esophageal cancer with clinical stage I-III and biopsy proof; patient with<br> cervical esophageal cancer or stage IV thoracic esophageal cancer could be recruited<br> in this trial according to Investigator's assessment.<br><br> 3. Complete first course CCRT with minimum doses of 40 Gy to tumor and nodal area via<br> external beam radiotherapy (EBRT).<br><br> 4. Patient whose tumor is resectable but declined to receive surgery after first course<br> CCRT.<br><br>Exclusion Criteria:<br><br> 1. T4b tumor status (tracheal / bronchial mucosa, aortic involvement, or fistula<br> formation).<br><br> 2. Stenosis of esophageal lumen that cannot be bypassed by the applicator.<br><br> 3. The primary tumor length exceeds 20cm.<br><br> 4. The patient is participating in other clinical trials.

Exclusion Criteria

Not provided

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To estimate the local control rate at primary tumor site

Secondary Outcome Measures

Name	Time	Method
Treatment toxicity grading according to the CTCAE