PACTR201909715467725已完成未知
Procalcitonin-guided antibiotic therapy for suspected and confirmed sepsis of patients in a surgical-trauma ICU: a prospective, two-period cross-over, interventional study
Rispah Chomba0 个研究点目标入组 80 人开始时间: 2019年9月4日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 80
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 19 Year(s) 至 44 Year(s)（—）
- 性别
- All
入选标准
- •Patients over the age of 18 years admitted to the trauma ICU with suspected or confirmed bacterial sepsis with written consent and who survived more than 48 hours after study inclusion.
排除标准
- •Patients in whom consent could not be obtained
- •Patients with severe co-morbidities e.g. congestive cardiac failure, cirrhosis, insulin dependent diabetes, chronic renal failure requiring dialysis, pregnancy and advanced HIV infection with CD4 ?100 cells/µL.
- •Patients requiring prolonged antibiotic therapy e.g. Clostridium difficile, Listeria monocytogenes, tuberculosis, fungal sepsis, osteomyelitis, lung abscess and sepsis involving a prosthetic device that could not be removed
- •Patients who had received antibiotics for more than 48 hours before enrollment
- •Patients with poor chance of survival (ISS score =45, injury critical or untreatable at screening).
研究者
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