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Clinical Trials/NCT03424837
NCT03424837
Completed
Not Applicable

Evaluation of the Impact of A Survivorship Care Plan and Embedded Navigation Tool (ASCENT) in Patients With Prostate Cancer Undergoing Curative-Intent Radiotherapy With Concurrent Androgen Deprivation Therapy (ADT)

Duke University6 sites in 1 country77 target enrollmentJanuary 11, 2019
ConditionsProstate Cancer

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Prostate Cancer
Sponsor
Duke University
Enrollment
77
Locations
6
Primary Endpoint
Abiding by the survivorship guidelines as measured by making an appointment within 6 months of enrollment OR completing a guideline-based assessment.
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

This is a parallel group, multisite prospective clinical study. The purpose of this study is to evaluate whether ASCENT enables patients to adhere to the survivorship guidelines and improves coordination of care to address patient needs.

Registry
clinicaltrials.gov
Start Date
January 11, 2019
End Date
November 24, 2020
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Male

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Histologically confirmed diagnosis of prostate adenocarcinoma
  • Age ≥18 years
  • Receiving curative intent radiotherapy for prostate cancer (Note: post-operative radiotherapy \[i.e., "adjuvant" or "salvage radiotherapy subsequent to prostatectomy\] is allowed.)
  • Subjects will be enrolled within two weeks prior to and two weeks after the final fraction of radiotherapy.
  • Receiving androgen deprivation therapy (ADT) for a duration of ≥3 consecutive months as follows:
  • GnRH agonist or antagonist (medical castration), with or without an anti-androgen (i.e., bicalutamide, flutamide, nilutamide, etc.), OR
  • Bilateral orchiectomy (surgical castration)
  • Technology requirement: candidates must have access to the internet
  • Able to understand and willing to sign a written informed consent document.
  • Able to speak and understand English, in the opinion of the treating physician.

Exclusion Criteria

  • Significant concurrent medical or psychiatric condition that would interfere with the patient's ability to abide by the study protocol or cooperate fully with the protocol requirements, including completion of survey and assessment

Outcomes

Primary Outcomes

Abiding by the survivorship guidelines as measured by making an appointment within 6 months of enrollment OR completing a guideline-based assessment.

Time Frame: 6 months

Abiding by the survivorship guidelines is defined as either of: Making an appointment with primary health care provider within 6 months of enrollment, OR completing a guideline-based assessment or management strategy for reducing side effects related to prostate cancer treatment.

Assess trial participants', caregivers'/family members', and staff satisfaction and experiences with the ASCENT technology and trial.

Time Frame: 6 months

Focus group comments and question responses detailing trial participants', caregivers'/family members', and staff's satisfaction and experiences with ASCENT.

Secondary Outcomes

  • Existence and severity of depression(6 months)
  • Overall health-related-quality of life including, but not limited to, mental and physical functioning as measured by the Short Form Health Survey(6 months)
  • General health status(6 months)
  • Prostate-cancer specific quality of life.(6 months)

Study Sites (6)

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