Aortic Cross Clamping Time, and Postoperative Respiratory Function
Not Applicable
Completed
- Conditions
- Bypass ComplicationRespiratory Complication
- Interventions
- Procedure: aortic cross clamping
- Registration Number
- NCT03072784
- Lead Sponsor
- Assiut University
- Brief Summary
Does the duration of cardiopulmonary bypass, and aortic cross clamping affects the post operative pulmonary function.
- Detailed Description
Cardiac surgery usually is done under cardiopulmonary bypass. As the blood contacts with the artificial tubing of the circuit, there is release of mediators which affects pulmonary function. Of no doubt that the duration of cardiopulmonary bypass, and cross clamping time, will affect the spell over of such mediators. Follow up of the pulmonary function, and arterial blood gas is mandatory in such group of patients.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 53
Inclusion Criteria
- adult patients
- elective open heart surgery
Exclusion Criteria
- Patients with myocardial ischemia or previous infarction
- low ejection fraction <30%
- history of AF
- implanted pacemaker
- uncontrolled hypertension
- renal impairment (creatinine >1.8 mg/dl)
- hepatic dysfunction
- insulin dependent diabetes
- chronic pulmonary disease
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description group S aortic cross clamping short time \<90 m aortic cross clamping group L aortic cross clamping \> 90 minutes aortic cross clamping
- Primary Outcome Measures
Name Time Method quality of oxygenation 48 hours postoperative PaO2 mmHg
- Secondary Outcome Measures
Name Time Method ventilation 48 hours postoperative respiratory rate (breath/minute)
carbon dioxide 48 hours PaCO2 mmhg
time to extubation 24 hours postoperative time to extubate in minutes
Trial Locations
- Locations (1)
Emad Zarief Kamel Said
🇪🇬Assiut, Egypt