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Clinical Trials/NCT03072784
NCT03072784
Completed
Not Applicable

Implication of Aortic Cross Clamping Time Upon Postoperative Respiratory Function in Adult Patients Undergoing Open Heart Surgery

Assiut University1 site in 1 country53 target enrollmentFebruary 1, 2015
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ConditionsBypass ComplicationRespiratory Complication

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Bypass Complication
Sponsor
Assiut University
Enrollment
53
Locations
1
Primary Endpoint
quality of oxygenation
Status
Completed
Last Updated
9 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

Does the duration of cardiopulmonary bypass, and aortic cross clamping affects the post operative pulmonary function.

Detailed Description

Cardiac surgery usually is done under cardiopulmonary bypass. As the blood contacts with the artificial tubing of the circuit, there is release of mediators which affects pulmonary function. Of no doubt that the duration of cardiopulmonary bypass, and cross clamping time, will affect the spell over of such mediators. Follow up of the pulmonary function, and arterial blood gas is mandatory in such group of patients.

Registry
clinicaltrials.gov
Start Date
February 1, 2015
End Date
August 25, 2016
Last Updated
9 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Emad Zarief , MD

Lecturer of Anesthesia and critical care Medicine

Assiut University

Eligibility Criteria

Inclusion Criteria

  • •adult patients
  • •elective open heart surgery

Exclusion Criteria

  • •Patients with myocardial ischemia or previous infarction
  • •low ejection fraction \<30%
  • •history of AF
  • •implanted pacemaker
  • •uncontrolled hypertension
  • •renal impairment (creatinine \>1.8 mg/dl)
  • •hepatic dysfunction
  • •insulin dependent diabetes
  • •chronic pulmonary disease

Outcomes

Primary Outcomes

quality of oxygenation

Time Frame: 48 hours postoperative

PaO2 mmHg

Secondary Outcomes

  • ventilation(48 hours postoperative)
  • carbon dioxide(48 hours)
  • time to extubation(24 hours postoperative)

Study Sites (1)

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