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Clinical Trials/NCT07556861
NCT07556861
Not yet recruiting
Not Applicable

Senyo Health App - Comorbid Substance Use Disorder Treatment In Bipolar Patients Using A Telehealth Collaborative Care Platform

Mayo Clinic1 site in 1 country40 target enrollmentStarted: May 16, 2026Last updated:

Overview

Phase
Not Applicable
Status
Not yet recruiting
Enrollment
40
Locations
1
Primary Endpoint
System Usability Scale (SUS) score

Overview

Brief Summary

The purpose of this study is to examine the effectiveness of a digital integrated behavioral health (IBH) platform in improving substance use outcomes, including treatment retention and substance use frequency and severity in patients with Bipolar Disorder.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • History of bipolar I disorder, bipolar II disorder, or schizoaffective disorder of the bipolar type
  • Alcohol use disorder.
  • Ability to read, write, and understand English;
  • Minimum DAST (1+) or AUDIT-C score (3+)
  • Access and willingness to use a mobile device for asynchronous (text) and synchronous (video) engagement with care;
  • Eligibility determined by ASAM Assessment

Exclusion Criteria

  • Diagnosed personality pathology as the primary presenting concern based on clinical judgment, severe cognitive impairment (e.g., intellectual disability or dementia), or psychosis;
  • Inability to actively participate in and learn from psychotherapeutic interaction based on clinical evaluation and clinical judgment;
  • Needing a higher level of mental health care as demonstrated by ASAM\[36\] assessment;
  • Decline to answer suicidality questions;
  • Already admitted into or about to initiate treatment in another addiction treatment program.
  • Currently attending High School.
  • Pregnancy confirmed by self-report

Arms & Interventions

Senyo Health app

Experimental

Patients will utilize the Senyo Health app daily, for 12 weeks

Intervention: Senyo Health App (Other)

Outcomes

Primary Outcomes

System Usability Scale (SUS) score

Time Frame: 12 weeks

The System Usability Scale (SUS) is a 10-item scale to assess usability of the app. Statements are rated on a 5 point scale where 1 = 'strongly disagree' and 5 = 'strongly agree'. Higher total scores indicates higher perception of app usability by patients.

Acceptability of Intervention Measure (AIM)

Time Frame: 12 weeks

The Acceptability of Intervention Measure (AIM) is a 12 question survey that assesses acceptability, appropriateness, and feasibility of the app. Responses are on a 5 point scale where 1 = 'completely disagree' and 5 = 'completely agree'. Higher scores indicate greater acceptance of the app.

Secondary Outcomes

  • Change in Brief Substance Craving Scale (BSCS) score(Baseline, weekly for 12 weeks, 4 months, 5 months, 6 months, 9 months, 12 months)
  • Change in Generalized Anxiety Disorder-7 (GAD-7) score(Baseline, weekly for 12 weeks, 4 months, 5 months, 6 months, 9 months, 12 months)
  • Change in Patient Health Questionnaire-9 (PHQ-9) score(Baseline, weekly for 12 weeks, 4 months, 5 months, 6 months, 9 months, 12 months)
  • Change in Patient Mania Questionnaire-9 (PMQ-9) score(Baseline, weekly for 12 weeks, 4 months, 5 months, 6 months, 9 months, 12 months)
  • Change in Brief Assessment of Recovery Capital (BARC-10) score(Baseline, 1 month, 2 months, 3 months, 4 months, 5 months, 6 months, 9 months, 1 year)

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Mark Frye

Principal Investigator

Mayo Clinic

Study Sites (1)

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