Skip to main content
MedPathMedPath Home
Clinical Trials/NCT00002410
NCT00002410
Completed
Phase 3

A Phase III, Multicenter, Randomized, Open-Label Study to Compare Antiretroviral Activity and Tolerability of Three Different Combination Regimens (DMP 266 + Indinavir, DMP 266 + Zidovudine + Lamivudine, Indinavir + Zidovudine + Lamivudine) in HIV-Infected Patients

Dupont Merck40 sites in 2 countriesAugust 31, 2001
Share to TwitterShare to FacebookShare to LinkedInShare to Reddit
ConditionsHIV Infections
DrugsIndinavir sulfateLamivudineZidovudine

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
HIV Infections
Sponsor
Dupont Merck
Locations
40
Status
Completed
Last Updated
20 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The purpose of this study is to compare the safety and effectiveness of three anti-HIV drug combinations. The three combinations are: (1) efavirenz (DMP 266) plus indinavir; (2) DMP 266 plus zidovudine (ZDV) plus lamivudine (3TC); and (3) indinavir plus ZDV plus 3TC. This study also examines the resistance HIV may have to these drugs and if these drugs are effective over a long period of time.

Registry
clinicaltrials.gov
Start Date
August 31, 2001
End Date
TBD
Last Updated
20 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Dupont Merck

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Not specified

Study Sites (40)

Loading locations...

Similar Trials

Completed
Phase 3
Comparison of Three Different Initial Treatments Without Protease Inhibitors for HIV InfectionHIV Infections
NCT00013520National Institute of Allergy and Infectious Diseases (NIAID)1,125
Completed
Phase 3
A Study to Evaluate the Use of a Protease Inhibitor and of Interleukin-2 (IL-2) in the Treatment of Early HIV InfectionHIV Infections
NCT00006154National Institute of Allergy and Infectious Diseases (NIAID)165
Terminated
Not Applicable
Safety and Effectiveness of 3 Anti-HIV Treatments in Patients Who Have Failed Previous Treatments Containing NelfinavirHIV Infections
NCT00006326Agouron Pharmaceuticals60
Completed
Phase 2
A Study to Compare The Ability of Different Anti-HIV Drugs to Decrease Viral Load After Nelfinavir (an Anti-HIV Drug)Treatment FailureHIV Infections
NCT00000918National Institute of Allergy and Infectious Diseases (NIAID)300
Completed
Phase 3
A Study to Compare Two Anti-HIV Drug Combinations in HIV-Infected Patients Who Have Previously Received Anti-HIV TreatmentHIV Infections
NCT00004581Abbott300