Protein Supplementation and Mixed Power Training on Muscle Function and Functional Capacities in Elderly Men

Not Applicable

Completed

• Conditions: Aging; Physical Impairment; Dynapenia
• Interventions: Other: Exercise + Placebo group; Other: Exercise + Protein group

• Registration Number: NCT03393650
• Lead Sponsor: Université du Québec a Montréal

Brief Summary

Investigate the effect of 12 weeks mixed power training (power and functional exercises) combined with a protein supplementation (30g/d) or not (placebo) on physiological characteristics of muscle and functional capacities in elderly men.

Detailed Description

Life habits are know to be able to prevent the loss of functional capacities and muscle function during aging process. More specifically, protein intake is important to maintain muscle function in older adults. Another non pharmacological intervention and well recognized for its efficacy, it's exercise training.

Recently, it has been observed than muscle quality is more important to maintain physical autonomy than muscle mass per se. In addition, muscle quality is more related to functional capacities than muscle mass.

Due to this recent finding, it has been proposed that muscle power training would be the best exercise intervention to prevent the loss of mobility.

Study Timeline

• Study Start: 2013-09
• Primary Completion: 2015-12
• Study Completion: 2015-12
• Study First Submitted: 2016-12-15
• Status Verified: 2018-01
• Study First Submitted QC: 2018-01-02
• Last Update Submitted: 2018-01-02
• Study First Posted: 2018-01-08
• Last Update Posted: 2018-01-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 100

Inclusion Criteria

• Elderly men
• 60 years and older
• Sedentary men
• Not obese (BMI <30 kg/m2)
• Living in free-living community

Exclusion Criteria

• Not able to follow an exercise program (doctor authorization: XAAP)
• Having Lactose intolerance
• Having Pace marker
• Having Metabolism disorder
• No weight stable since the last 6 months
• No stable medication (same dose and type since at least 6 months)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Exercise + Placebo group	Exercise + Placebo group	50 subjects will receive a placebo supplementation with an exercise intervention (EX group)
Exercise + Protein group	Exercise + Protein group	50 subjects will receive a protein supplementation combined with an exercise intervention (PROTEX group)

Primary Outcome Measures

Name	Time	Method
Change in walking speed	Change from Baseline walking speed at 12 weeks measure in all subjects	evaluate using the 4m- normal walking speed (m/sec)

Secondary Outcome Measures

Name	Time	Method
Change in lower limb muscle quality	Change from Baseline lower limb muscle quality at 12 weeks measure in all subjects	Knee extension muscle strength (isometric (N)/ lower limb muscle mass (kg))