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Clinical Trials/ACTRN12624000400561
ACTRN12624000400561
Not yet recruiting
未知

Coronary Artery disease SCreening in young ADult relativEs of individuals with premature Myocardial Infarction (CASCADE-MI study)

Curtin University0 sites300 target enrollmentApril 3, 2024

Overview

Phase
未知
Intervention
Not specified
Conditions
Myocardial infarction
Sponsor
Curtin University
Enrollment
300
Status
Not yet recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
April 3, 2024
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Apparently healthy first\-degree relative aged 30 to 55 years of a patient with myocardial infarction at premature age (\<55 years).

Exclusion Criteria

  • Exclusion criteria for the apparently healthy relative will include:
  • History of cardiovascular disease (i.e., coronary artery disease, peripheral arterial disease, or cerebrovascular disease).
  • Already taking aspirin or statin.
  • History of iodinated contrast allergy/anaphylaxis.
  • Known renal impairment with estimated glomerular filtration rate \<45 ml/min/1\.73m2\.
  • Unwilling or unable to provide informed consent.
  • Pregnant women.
  • Exclusion criteria for the index case (patient) will include the following diagnoses:
  • Non\-atherosclerotic cause of myocardial infarction such as spontaneous coronary artery dissection, paradoxical venous thrombo\-embolism, myocarditis, pericarditis, vasospasm, and Takotsubo cardiomyopathy.
  • Myocardial infarction with nonobstructive coronary arteries.

Outcomes

Primary Outcomes

Not specified

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