ACTRN12624000400561
Not yet recruiting
未知
Coronary Artery disease SCreening in young ADult relativEs of individuals with premature Myocardial Infarction (CASCADE-MI study)
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Myocardial infarction
- Sponsor
- Curtin University
- Enrollment
- 300
- Status
- Not yet recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Apparently healthy first\-degree relative aged 30 to 55 years of a patient with myocardial infarction at premature age (\<55 years).
Exclusion Criteria
- •Exclusion criteria for the apparently healthy relative will include:
- •History of cardiovascular disease (i.e., coronary artery disease, peripheral arterial disease, or cerebrovascular disease).
- •Already taking aspirin or statin.
- •History of iodinated contrast allergy/anaphylaxis.
- •Known renal impairment with estimated glomerular filtration rate \<45 ml/min/1\.73m2\.
- •Unwilling or unable to provide informed consent.
- •Pregnant women.
- •Exclusion criteria for the index case (patient) will include the following diagnoses:
- •Non\-atherosclerotic cause of myocardial infarction such as spontaneous coronary artery dissection, paradoxical venous thrombo\-embolism, myocarditis, pericarditis, vasospasm, and Takotsubo cardiomyopathy.
- •Myocardial infarction with nonobstructive coronary arteries.
Outcomes
Primary Outcomes
Not specified
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