Evaluation of the effect of high protein nutritional support in comparison to nutritional support with regular protein intake in intensive care unit patients: a double-blind randomized clinical trial

Mashhad University of Medical Sciences0 个研究点目标入组 60 人开始时间: 待定最近更新: 2019年12月17日

适应症

试验速览

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•=18 years old
•Nutritionally ‘high-risk”: Moderate to severe malnutrition (as defined by local assessments), BMI=25, Frailty (Clinical Frailty Scale 5 or more). Sarcopenia- (SARC-F score of 4 or more).
•Patients who have been ventilated for at least the first 48 hours of admission or expect ventilation to last more than 4 days.
•Completion of informed consent form in the first stage of legal guardianship in case of failure in this field to the judge.
•Ability to enteral feed in the first 24 to 48 hours of admission.
•Lack of participation in any other interventional research project.

•>96 continuous hours of mechanical ventilation before the screening
•Expected death or withdrawal of life-sustaining treatments within 7 days from admission
•The responsible clinician recognizes that the patient either needs low or high protein regimen
•Patients require only parenteral nutrition
•History of diseases such as hepatocirrhosis and End-stage renal disease.

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