Exploring the potential of Hybrid Electrical Stimulation Cycling for aerobic exercise in Persons with Advanced Multiple Sclerosis

Not Applicable

Recruiting

• Conditions: Multiple Sclerosis; Neurological - Multiple sclerosis; Physical Medicine / Rehabilitation - Other physical medicine / rehabilitation

• Registration Number: ACTRN12617000415303
• Lead Sponsor: Dr Che Fornusek

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-03-23
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

Diagnosis of advanced multiple sclerosis - EDSS 6.0-8.5 inclusive
Not able to walk 25m without the assistance of a cane
Ability to perform arm cranking exercise
Aged 18-65 years
Male or female

Exclusion Criteria

Participants will be excluded if their doctor believes there is any reason they cannot safely participate in this study due to other conditions or absolute contradictions to exercise.
People who have contraindications to functional electrical stimulation cycling exercise which include:
i.having an a demand-type implanted cardiac pacemaker or defibrillator or deep brain stimulator
ii.people who reacts very negatively to the experience or to the sensation of stimulation.
iii.people with undiagnosed pain.
iv.people who cannot provide adequate feedback concerning the level of stimulation
v. people who have a serious cognitive impairment.
vi. people who have had a multiple sclerosis exacerbation in the last three months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Peak oxygen consumption during each exercise trial. Measured by breath by breath analysis using a metabolic cart.[Measured continuously throughout each trial]

Secondary Outcome Measures

Name	Time	Method
Maximum heart rate during each exercise trial. Measured by Polar watch and electrode strap[measured continuously throughout each trial];perception of fatigue (Likert scale) [Immediately Post trial A, B, & C];Perception of effort fatigue (modified Borg 10-point scale) [Immediately Post Trial A, B, & C]