A clinical trial to compare the effect of two drugs, dexmedetomidine and esmolol as blood pressure controlling agents in patients undergoing ENT surgeries.
Phase 3
- Conditions
- Health Condition 1: null- ASA grade I-II patients of both sexes aged between 18-60 yrs, undergoing Otorhinolaryngeal (ENT) surgeries.
- Registration Number
- CTRI/2017/03/008077
- Lead Sponsor
- Dr Shilpa bansal
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Patients aged 18- 60 yrs of both the sexes, undergoing planned Otorhinolaryngeal (ENT) surgeries with ASA grade I-II.
Exclusion Criteria
1.Patients refusing to give informed consent.
2.Patients with recurrent sinus surgery and patients with systemic co-morbidities like hypertension, coronory artery disease, renal or hepatic disease, cerebro vascular accidents.
3.Patients with coagulopathies or receiving drugs which have effects on coagulation profile.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method primary outcome is to compare the quality of the surgical field using a predefined category scaleTimepoint: surgical field score
- Secondary Outcome Measures
Name Time Method compare the efficacy and safety of dexmedetomidine with Esmolol as a hypotensive agent in ENT surgeries with attention on analgesia requirement, recovery profile, and tolerability in adult patients.Timepoint: sedation score, visual analogue score, modified aldrete score