The Pleiotropic Effects of Atorvastatin When Combined With Common Antihypertenisve Medications.

Not Applicable

Withdrawn

• Conditions: Hypertension
• Interventions: Drug: Amlodipine and Hydrocholorothiazide

• Registration Number: NCT00656331
• Lead Sponsor: University of New Mexico

Brief Summary

The purpose of this study is to compare the effects of the cholesterol medication taken with each blood pressure medication alone on heart disease risk factors including blood pressure, cholesterol, inflammation, blood sugar control, blood vessal function, and other heart disease risk factors.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-08
• Study First Submitted: 2008-04-07
• Study First Submitted QC: 2008-04-07
• Study First Posted: 2008-04-11
• Primary Completion: 2012-06
• Study Completion: 2012-06
• Status Verified: 2023-07
• Last Update Submitted: 2023-07-07
• Last Update Posted: 2023-07-11

Recruitment & Eligibility

• Status: WITHDRAWN
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

• mild hypertension and high cholesterol

Exclusion Criteria

• diabetes and heart disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
1	Amlodipine and Hydrocholorothiazide	Amlodipine
2	Amlodipine and Hydrocholorothiazide	HCTZ

Primary Outcome Measures

Name	Time	Method
PAI-1	study completion

Trial Locations

Locations (1)

UNMHSC; 🇺🇸 Albuquerque, New Mexico, United States