Comparison of The Effect of A-PRF and L-PRF Application to The Palatal Region on Quality of Life and Wound Healing After Free Gingival Graft Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Palate; Wound
- Sponsor
- Izmir Katip Celebi University
- Enrollment
- 36
- Locations
- 1
- Primary Endpoint
- Epithelialization
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Different approaches are used to reduce post-operative complications associated with the palatal wound site after free gingival graft (FGG) harvesting. The aim of this study was to compare the effects of L-PRF and A-PRF on palatal wound healing after free gingival graft harvesting and patients' quality of life.
Detailed Description
Thirty-six patients between the ages of 18 and 60 years (11 males and 25 females) who had completed Phase 1 periodontal treatments and for whom FGG surgery was indicated for isolated gingival recession defects limited to one or two teeth with shallow vestibule and insufficient keratinized or attached gingival width were included in the present study. Three different treatments were performed on palatal wound areas: L-PRF (L-PRF group, n = 12), A-PRF (A-PRF group, n = 12) and palatal stent (control group, n = 12) OHIP-14 scores, VAS scores (for pain), analgesic tablet intake, and epithelialization condition were recorded for different time points.
Investigators
Prof.Dr. Mehmet Sağlam
Principle Investigator
Izmir Katip Celebi University
Eligibility Criteria
Inclusion Criteria
- •Patients ≥18 years requiring FGG surgery because of shallow vestibule and insufficient keratinized/attached gingival width
Exclusion Criteria
- •no smoking /no alcohol use,
- •not suffering from any systemic disease that could impair the healing of wounds,
- •pregnancy or lactation,
- •Previous graft harvesting from the same site.
Outcomes
Primary Outcomes
Epithelialization
Time Frame: 1 month
Hydrogen peroxide (H2O2) test was used to evaluate the integrity of epithelialization
Secondary Outcomes
- Pain at Palatal wound area(First 7 days)
- Oral health-related quality of life (OHRQoL)(7 and 14 days after free gingival graft surgery)