Analysis of Oxidative Stress Biomarkers and Their Determinants in ART-experienced PLWH
Recruiting
- Conditions
- HIV Infections
- Interventions
- Other: blood sampling
- Registration Number
- NCT05760495
- Brief Summary
The project aims to assess the level of oxidative stress biomarkers in HIV patients on effective antiretroviral treatment in correlation with other therapeutic, clinical, and viro- immunological parameters. The analysis aims to better characterize the patient on treatment through an innovative approach based on two specific tests for complementary assessment of total oxidant and anti-oxidant plasma capacity.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 543
Inclusion Criteria
- ART-treated PLWH
- HIV-1 RNA< 50 copies/mL
- Stable ART therapy (at least 48 weeks)
- Signature of informed consent for study participation
Exclusion Criteria
- none
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Single arm blood sampling ART-experienced PLWH
- Primary Outcome Measures
Name Time Method Assessment of the levels of total oxidant and antioxidant plasma capacity 1 year Quantify the levels of total oxidant and antioxidant plasma capacity antioxidant
- Secondary Outcome Measures
Name Time Method Correlation between level of oxidative stress biomarkers and several factors 1 year Evaluation of the impact of therapeutic, viro-immunologic, clinical, and demographic factors on the level of oxidative stress biomarkers.
Trial Locations
- Locations (1)
Francesca Lombardi
🇮🇹Roma, RM, Italy