IV dexmeditomidine prior to intubation

Not yet recruiting

• Conditions: ASA I and II patients; Medical and Surgical, (2) ICD-10 Condition: O||Medical and Surgical, (3) ICD-10 Condition: O||Medical and Surgical, (4) ICD-10 Condition: O||Medical and Surgical,

• Registration Number: CTRI/2021/10/037428
• Lead Sponsor: Dr Waseema Kabeer

Brief Summary

It is a randomised,prospective,comparative,double blinded, observational study wherein Two doses of IV dexmeditomidine are compared for the attenuation of hemodynamic pressor response of laryngoscopy and endotracheal intubation before any surgical procedure in the operation theatre.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-01-11
• Last Update Posted: 2021-10-20

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Age between 18-60 yr of either sex.
• ASA grade I and grade II.
• Patients posted for elective surgeries under general anesthesia requiring intubation.
• Hemodynamically stable patients having all routine investigations within normal limits.
• Patients who give written informed consent and are willing to be part of the study.

Exclusion Criteria

• Patients refusal.
• Patients with ASA physical status III and more.
• Patients with any pre-existing cardiovascular disease.
• Patients with h/o allergy to test drugs.
• Patients posted for emergency surgeries.
• Patients with difficult airway.
• Patients with neurological disorders and muscle diseases.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To observe the attenuation of pressor response to laryngoscopy and endotracheal intubation with IV dexmedetomindine	PRE SCOPE, AT THE TIME OF SCOPY, 0 MINS, 5 MINS, EVERY 5 MINUTES UPTO 2 HOURS, POST EXTUBATION VAS

Secondary Outcome Measures

Name	Time	Method
To observe the attenuation of pressor responses to laryngoscopy and endotracheal intubation with intravenous Dexmeditomidine 1mcg/kg	PRE SCOPE, AT THE TIME OF SCOPY, 0 MINS, 5 MINS, EVERY 5 MINUTES UPTO 2 HOURS, POST EXTUBATION VAS

Trial Locations

Locations (1)

Dr. DY Patil medical college; 🇮🇳 Pune, MAHARASHTRA, India

Dr. DY Patil medical college

🇮🇳Pune, MAHARASHTRA, India

Dr Waseema Kabeer

Principal investigator

9884028248

waseema040194@gmail.com