A Comparison of Olopatadine and Fluticasone in Patients With Allergic Conjunctivitis
Phase 4
Completed
- Conditions
- Conjunctivitis, Allergic
- Interventions
- Registration Number
- NCT00655109
- Lead Sponsor
- Greiner, Jack V., OD DO PhD
- Brief Summary
To compare the clinical efficacy of olopatadine and fluticasone in a 3-week single center, double-masked, randomized, placebo controlled parallel treatment conjunctival allergen challenge (CAC) study in patients with allergic conjunctivitis
- Detailed Description
Study will evaluate the efficacy of nasal anti-allergic therapy compared to ocular anti-allergic therapy in the prevention of ocular allergic symptoms.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- At least 18 years of age & either sex, any race
- Willing and able to follow all instructions and attend all study visits
- Positive history of ocular allergies
- Reproducible positive ocular allergic reaction induced by conjunctival allergen challenge
Exclusion Criteria
- Have planned surgery during trial period
- Female currently pregnant, planning a pregnancy, or lactating
- Use of disallowed medications
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 3 Saline Placebo nasal spray 4 Artificial tears Placebo Eyedrops 1 Olopatadine Olopatadine 2 Fluticasone Fluticasone
- Primary Outcome Measures
Name Time Method Ocular itching Minutes following CAC
- Secondary Outcome Measures
Name Time Method Ocular redness Minutes following CAC
Trial Locations
- Locations (1)
Ophthalmic Research Associates, Inc
🇺🇸North Andover, Massachusetts, United States