NL-OMON55682RecruitingPhase 4
Pharmacogenetics Use For Further treatment Improvement in childreN - PUFFI
Conditions
Trial Snapshot
- Phase
- Phase 4
- Status
- Recruiting
- Sponsor
- Academisch Medisch Centrum
- Enrollment
- 100
Study Overview
Brief Summary
Trial is onging in other countries
Study Design
- Study Type
- Interventional
Eligibility Criteria
- Ages
- 2 to 17 (—)
Inclusion Criteria
- •- Between 6-18 years of age
- •- Doctor's diagnosis of asthma based on patient history, FEV1 reversibility >=
- •12% ever and/or bronchial hyperresponsiveness ever.
- •- Current asthma symptoms (based on ACT (>= 12 years) or c-ACT (< 12 years)
- •score <= 19
- •- ICS use >= 3 months before inclusion (start dosage ICS, treatment step 2
- •according to childhood asthma guideline NVK)
- •- Adequate inhalation technique
- •- self-assessed good adherence to maintenance asthma treatment
- •- understanding of Dutch language
- •- Internet access at home, willing to fill in internet questionnaires
Exclusion Criteria
- •- active smoking
- •- congenital heart disease
- •- serious lung disease other than asthma
- •- LABA use in the past 6 months
- •- omalizumab use
- •- ICU admission in the previous year
Investigators
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