Early neuronal processing of basic tastes in healthy young adults and elderly, investigated with fMRI.

Completed

• Conditions: physiological processing of taste; Taste disturbance; 10003018

• Registration Number: NL-OMON39437
• Lead Sponsor: niversitair Medisch Centrum Groningen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 80

Inclusion Criteria

Caucasian
Age range young: 18-30
Age range elderly: 60-75
Young women: using hormonal anti conceptives

Exclusion Criteria

MR incompatable (posibility of any incompatible metal objects inside the body)
History of psychiatric disorders
History of taste-related disorders
Smokers
Wearing glasses (lenses are allowed)
Alcohol/drug abuse
Pregnancy
Users of removable dentures, will be asked to remove these before the experiment.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The outcomes of the study will consist of:<br /><br>- The neural activity due to the ingestion of the basic tastes: sweet salty,<br /><br>sour and/or bitter.<br /><br>- The behavioral response related to them.<br /><br>- The results of the application of machine learning and other cognitive<br /><br>modelling techniques to these data (behavioral + brain activity).<br /><br>- A description of the functional organization within the brain as a function<br /><br>of the early neuronal processing of to basic tastes.<br /><br>- A description of the emotional reactions and its temporal dynamics. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Not applicable.</p><br>