Clinical Effect of Phenytoin Mucoadhesive Paste on Wound Healing After Oral Biopsy

Phase 1

• Conditions: Wound Healing; Pain
• Interventions: Drug: Phenytoin paste; Drug: Placebo

• Registration Number: NCT01680042
• Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary

several studies have investigated healing effect of phenytoin.In this study we investigate healing effect of phenytoin mucoadhesive paste comparing to the usual mucoadhesive paste after oral biopsy.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2012-09-03
• Study First Submitted QC: 2012-09-05
• Study First Posted: 2012-09-06
• Status Verified: 2012-10
• Study Start: 2012-10
• Last Update Submitted: 2012-10-01
• Last Update Posted: 2012-10-02
• Primary Completion: 2013-03

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• patients undergone oral biopsy

Exclusion Criteria

• systemic disease

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
phenytoin paste	Phenytoin paste	this group receives phenytoin paste after oral biopsy
usual mucoadhesive paste	Placebo	this group receives the usual mucoadhesive paste without phenytoin after oral biopsy

Primary Outcome Measures

Name	Time	Method
healing biopsy wound	7 days	patient recieves phenytoin mucoadhesive paste after oral biopsy and the diameter of inflammatory halo is determined in 1,3,5and the 7th days.pain measurment is also assesed by VAS score

Trial Locations

Locations (2)

Shahid Beheshti Medical University; 🇮🇷 Tehran, Iran, Islamic Republic of

Shaheed Beheshti University; 🇮🇷 Tehran, Iran, Islamic Republic of