Influence of Extracorporeal Circulation on the Development of OSA (Obstructive Sleep Apnea)
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Coronary Artery Disease
- Sponsor
- Astes
- Primary Endpoint
- Change in the AHI
- Status
- Withdrawn
- Last Updated
- 6 years ago
Overview
Brief Summary
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- Coronary artery bypass grafting (CABG) could be performed with or without extracorporeal circulation (ECC).
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- OSA (Obstructive Sleep Apnea) could be influenced by in intravenous perfusion.
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- ECC could influence the amount of intravenous perfusion administered to the patient.
The aim of this study was to examine the influence of ECC on the development of OSA.
Detailed Description
* 1. Coronary artery bypass grafting (CABG) could be performed with or without extracorporeal circulation (ECC). * 2. OSA (Obstructive Sleep Apnea) could be influenced by in intravenous perfusion. * 3. ECC could influence the amount of intravenous perfusion administered to the patient. The aim of this study was to examine the influence of ECC on the development of OSA. The AHI (Apnea Hypopnea Index) will be used to assess this potential influence.
Investigators
Eric DEFLANDRE, MD, PhD, FCCP, FAHA
Head of Department
Astes
Eligibility Criteria
Inclusion Criteria
- •All of the patients scheduled for an elective CABG
Exclusion Criteria
- •Patient's refusal
Outcomes
Primary Outcomes
Change in the AHI
Time Frame: 3 days
Change from baseline AHI (Apnea Hypopnea Index, which is the average amount of apnea and hypopnea per four of sleep) at the 3rd postoperative day. The AHI is derived from the polysomnography which will be performed to all of the patients the day before surgery and the 3rd postoperative day.