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Clinical Trials/NCT01300117
NCT01300117
Unknown
Not Applicable

Influence of Extracorporeal Circulation During Cardiac Surgery on the Development of Postoperative TTP

Johann Wolfgang Goethe University Hospital1 site in 1 country70 target enrollmentOctober 2010
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ConditionsCardiac Surgery

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cardiac Surgery
Sponsor
Johann Wolfgang Goethe University Hospital
Enrollment
70
Locations
1
Primary Endpoint
Change in ADAMTS13-Activity over time
Last Updated
14 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The purpose of this study is to determine whether extracorporeal circulation during cardiac surgery has an influence on ADAMTS13-Activity.

Registry
clinicaltrials.gov
Start Date
October 2010
End Date
TBD
Last Updated
14 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Johann Wolfgang Goethe University Hospital

Eligibility Criteria

Inclusion Criteria

  • •cardiac surgery with or without (OPCAB) the use of extracorporeal circulation
  • •patient agrees

Exclusion Criteria

  • •no agreement
  • •known TTP in medical history

Outcomes

Primary Outcomes

Change in ADAMTS13-Activity over time

Time Frame: during surgery (at 1and 2 hours after beginning) and within the first 6 days after surgery

Secondary Outcomes

  • Change in ADAMTS13-Antibody over time(during surgery (at 1and 2 hours after beginning) and within the first 6 days after surgery)
  • Change in Platelet count over time(during surgery (at 1and 2 hours after beginning) and within the first 6 days after surgery)
  • time duration of extracorporeal circulation during surgery(during surgery)
  • Amount of intraoperative given fluid replacement(during surgery)
  • Amount of given blood products (red blood cells)(24 hours)

Study Sites (1)

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