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Clinical Trials/NCT05631951
NCT05631951
Active, not recruiting
Not Applicable

Bone Transport Through Induced Membrane Technique Versus Conventional Bone Transport Technique in Management of Bone Defects of Lower Limbs

Ain Shams University1 site in 1 country30 target enrollmentStarted: January 1, 2019Last updated:
ConditionsBone Loss

Overview

Phase
Not Applicable
Status
Active, not recruiting
Enrollment
30
Locations
1
Primary Endpoint
complications rate

Overview

Brief Summary

This is a prospective randomised controlled comparative study comparing bone transport through induced membrane (BTM) and conventional bone transport (BT) in management of bone defects in infected non united fractures of long bones of lower limbs (femur, tibia) as regard clinical, functional outcomes and possible complications.

Detailed Description

A prospective randomised controlled study was conducted at Ain shams university hospitals. A total of 30 patients with infected non united fractures of long bones of lower limbs (femur and tibia) were divided randomly into 15 patients treated by bone transport through induced membrane technique (BTM) (Group A) and 15 patients treated by conventional bone transport technique (BT) (Group B)

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to 60 Years (Adult)
Sex
All
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • Sex: both sexes.
  • Age:18-60 yrs old.
  • Lesion: tibial or femoral bone defects (\>4 cm)
  • Defects resulting from infected non-united fractures

Exclusion Criteria

  • Pathological and congenital defects
  • Aseptic traumatic bone defects
  • Defects less than 4 cm
  • Multiple defects Pediatric age group

Outcomes

Primary Outcomes

complications rate

Time Frame: through study completion, an average of 1 year

number of complications in each group

additional operations

Time Frame: through study completion, an average of 1 year

number of additional operations in each group

External fixation time

Time Frame: through study completion, an average of 1 year

time from the initial application of the fixator until removal of fixator (in months)

Association for the Study and Application of the Method of Ilizarov (ASAMI) Scoring System

Time Frame: through study completion, an average of 1 year

scoring system for bone and functional results

External fixation index

Time Frame: through study completion, an average of 1 year

calculated by dividing the EFT (months) by the bone defect size (centimeters)

Docking time

Time Frame: through study completion, an average of 1 year

time taken (months) from end of bone transport till union of docking site (both with and without bone graft)

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Sponsor

Study Sites (1)

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