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Extension Study to Assess Persistence of Benefit of LibiGel for the Treatment of Hypoactive Sexual Desire Disorder (HSDD)

Phase 3
Completed
Conditions
Hypoactive Sexual Desire Disorder
Interventions
Registration Number
NCT01235754
Lead Sponsor
BioSante Pharmaceuticals
Brief Summary

The objective of this study is to evaluate the persistence of benefit of LibiGel (testosterone gel) 300 mcg/day compared to placebo gel in a 12 week post-treatment period of Hypoactive Sexual Desire Disorder (HSDD) in surgically menopausal women.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
626
Inclusion Criteria
  • must have completed a minimum of 22 weeks of the 24-week TESTW006 or TESTW008 clinical trial
Exclusion Criteria
  • Any condition (including a change in sexual or relationship history) that would make the subject unsuitable for participation in the trial in the opinion of the Investigator

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
placebo gelplacebo gelplacebo transdermal gel
testosterone geltransdermal testosterone gel 1%transdermal testosterone gel
Primary Outcome Measures
NameTimeMethod
Change in the 4-week total number of days with at least one satisfying sexual event from the baseline period (during the previous study) to weeks 9-12 of the current study12 weeks

This study is to assess the persistence of benefit following the withdrawal of testosterone gel (LibiGel) in the treatment of Hypoactive Sexual Desire Disorder (HSDD) in healthy, surgically menopausal women.

Secondary Outcome Measures
NameTimeMethod
change from baseline (previous study) in the mean FSDS-R question 13 score to week 12 of the current study12 weeks

This study is to acess the persistence of benefit following the withdrawal of testosterone gel 1% (LibiGel)in the treatment of Hypoactive Sexual Desire Disorder (HSDD) in healthy, surgically menopausal women.

change from baseline (previous study) in the total number of days with at least one satisfying sexual event at weeks 4 and 8 of the current study12 weeks

This study is to assess the persistence of benefit following the withdrawal of testosterone gel (LibiGel)in the treatment of Hypoactive Sexual Desire Disorder (HSDD) in healthy, surgically menopausal women.

Trial Locations

Locations (102)

BioSante Site #101

🇺🇸

Cleveland, Ohio, United States

BioSante Site #128

🇺🇸

Seattle, Washington, United States

BioSante Site #024

🇺🇸

Miami, Florida, United States

BioSante Site #122

🇺🇸

Houston, Texas, United States

BioSante Site #008

🇺🇸

San Diego, California, United States

BioSante Site #212

🇺🇸

Cincinnati, Ohio, United States

BioSante Site #211

🇺🇸

San Antonio, Texas, United States

BioSante Site #163

🇺🇸

Overland Park, Kansas, United States

BioSante Site #121

🇺🇸

Phoenix, Arizona, United States

BioSante Site #044

🇺🇸

Detroit, Michigan, United States

BioSante Site #042

🇺🇸

Nashville, Tennessee, United States

BioSante Site #102

🇺🇸

Salt Lake City, Utah, United States

BioSante Site #146

🇺🇸

Mobile, Alabama, United States

BioSante Site #095

🇺🇸

Hoover, Alabama, United States

BioSante Site #086

🇺🇸

Norfolk, Virginia, United States

BioSante Site #120

🇺🇸

North Jackson, Tennessee, United States

BioSante Site #052

🇺🇸

Hot Springs, Arkansas, United States

BioSante Site #096

🇺🇸

Williston, Vermont, United States

BioSante Site #039

🇺🇸

Houston, Texas, United States

BioSante Site #154

🇺🇸

Hurst, Texas, United States

BioSante Site #053

🇺🇸

Richmond, Virginia, United States

BioSante Site #183

🇺🇸

Walla Walla, Washington, United States

BioSante Site #048

🇺🇸

Austin, Texas, United States

BioSante Site #144

🇺🇸

Pleasant Grove, Utah, United States

BioSante Site #003

🇺🇸

Charlottesville, Virginia, United States

BioSante Site #073

🇺🇸

Corpus Christi, Texas, United States

BioSante Site #083

🇺🇸

Mountlake Terrace, Washington, United States

BioSante Site #220

🇺🇸

Dallas, Texas, United States

BioSante Site #218

🇺🇸

Murray, Utah, United States

BioSante Site #054

🇨🇦

Windsor, Ontario, Canada

BioSante Site #007

🇺🇸

Denver, Colorado, United States

BioSante Site #193

🇨🇦

Shawinigan, Quebec, Canada

BioSante Site #145

🇺🇸

Glendale, Arizona, United States

BioSante Site #171

🇺🇸

Chandler, Arizona, United States

BioSante Site #014

🇺🇸

Huntsville, Alabama, United States

BioSante Site #027

🇺🇸

Glendale, Arizona, United States

BioSante Site #137

🇺🇸

Tucson, Arizona, United States

BioSante Site #155

🇺🇸

Little Rock, Arkansas, United States

BioSante Site #221

🇺🇸

Berkeley, California, United States

BioSante Site #182

🇺🇸

Buena Park, California, United States

BioSante Site #162

🇺🇸

Sacramento, California, United States

BioSante Site #132

🇺🇸

New Britain, Connecticut, United States

BioSante Site #159

🇺🇸

Walnut Creek, California, United States

BioSante Site #026

🇺🇸

Lakewood, Colorado, United States

BioSante Site #036

🇺🇸

Ridgefield, Connecticut, United States

BioSante Site #151

🇺🇸

New London, Connecticut, United States

BioSante Site #143

🇺🇸

Jacksonville, Florida, United States

BioSante Site #111

🇺🇸

Orlando, Florida, United States

BioSante Site #219

🇺🇸

Pinellas Park, Florida, United States

BioSante Site #041

🇺🇸

St. Petersburg, Florida, United States

BioSante Site #009

🇺🇸

West Palm Beach, Florida, United States

BioSante Site #115

🇺🇸

Atlanta, Georgia, United States

BioSante Site #202

🇺🇸

Idaho Falls, Idaho, United States

BioSante Site #017

🇺🇸

Meridian, Idaho, United States

BioSante Site #189

🇺🇸

Addison, Illinois, United States

BioSante Site #133

🇺🇸

Chicago, Illinois, United States

BioSante Site #167

🇺🇸

Newburgh, Indiana, United States

BioSante Site #214

🇺🇸

Lexington, Kentucky, United States

BioSante Site #110

🇺🇸

Metarie, Louisiana, United States

BioSante Site #005

🇺🇸

Shreveport, Louisiana, United States

BioSante Site #206

🇺🇸

Fall River, Massachusetts, United States

BioSante Site #124

🇺🇸

Bingham Farms, Michigan, United States

BioSante Site #047

🇺🇸

Grand Rapids, Michigan, United States

BioSante Site #031

🇺🇸

St. Clair Shores, Michigan, United States

BioSante Site #105

🇺🇸

Kalamazoo, Michigan, United States

BioSante Site #033

🇺🇸

Saginaw, Michigan, United States

BioSante Site #059

🇺🇸

Cary, North Carolina, United States

BioSante Site #015

🇺🇸

Poughkeepsie, New York, United States

BioSante Site #130

🇺🇸

Beachwood, Ohio, United States

BioSante Site #104

🇺🇸

St. Louis, Missouri, United States

BioSante Site #208

🇺🇸

Edina, Minnesota, United States

BioSante Site #107

🇺🇸

Raleigh, North Carolina, United States

BioSante Site #131

🇺🇸

Winston-Salem, North Carolina, United States

BioSante Site #006

🇺🇸

Lincoln, Nebraska, United States

BioSante Site #198

🇺🇸

St. Paul, Minnesota, United States

BioSante Site #056

🇺🇸

Fargo, North Dakota, United States

BioSante Site #210

🇺🇸

Akron, Ohio, United States

BioSante Site #160

🇺🇸

Englewood, Ohio, United States

BioSante Site #213

🇺🇸

Columbus, Ohio, United States

BioSante Site #129

🇺🇸

Tulsa, Oklahoma, United States

BioSante Site #138

🇺🇸

West Chester, Ohio, United States

BioSante Site #153

🇺🇸

Gallipolis, Ohio, United States

BioSante Site #106

🇺🇸

Eugene, Oregon, United States

BioSante Site #099

🇺🇸

Sellersville, Pennsylvania, United States

BioSante Site #165

🇺🇸

Jenkintown, Pennsylvania, United States

BioSante Site #050

🇺🇸

Eugene, Oregon, United States

BioSante Site #126

🇺🇸

Medford, Oregon, United States

BioSante Site #117

🇺🇸

Anderson, South Carolina, United States

BioSante Site #197

🇺🇸

Wexford, Pennsylvania, United States

BioSante Site #089

🇺🇸

Columbia, South Carolina, United States

BioSante Site #069

🇺🇸

Chattanooga, Tennessee, United States

BioSante Site #078

🇺🇸

Memphis, Tennessee, United States

BioSante Site #147

🇺🇸

Dallas, Texas, United States

BioSante Site #181

🇺🇸

Tacoma, Washington, United States

BioSante Site #188

🇨🇦

Sarnia, Ontario, Canada

BioSante Site #035

🇺🇸

Ann Arbor, Michigan, United States

BioSante Site #209

🇺🇸

Greer, South Carolina, United States

BioSante Site #049

🇺🇸

Watertown, South Dakota, United States

BioSante Site #141

🇺🇸

Roswell, Georgia, United States

BioSante Site# 123

🇨🇦

Ottawa, Ontario, Canada

BioSante Site #127

🇺🇸

Billings, Montana, United States

BioSante Site #051

🇺🇸

Missoula, Montana, United States

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