MedPath

Joint distraction in the treatment of knee osteoarthritis: efficacy and underlying mechanisms.

Completed
Conditions
Osteoarthritis of the knee is a progressing degenerative joint disorder, characterised by joint pain and limitation of movement, leading to disability. Tissue changes comprise damage of joint cartilage, synovial inflammation and changes in subchondral bone, such as subchondral sclerosis and osteophyte formation (bony outgrowths).
Registration Number
NL-OMON20489
Lead Sponsor
niversity Medical Center Utrecht,Rheumatology & Clin. Immunology and Orthopaedics
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
3
Inclusion Criteria

1. Age < 55 years;

2. Osteoarthritis, primary in the tibio-femoral joint, uni or bilateral;

Exclusion Criteria

1. Osteoarthritis in both knees;

2. Primary retro-patellar osteoarthritis;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Pain (according to the WOMAC).
Secondary Outcome Measures
NameTimeMethod
Functional disability (according to the WOMAC).
© Copyright 2025. All Rights Reserved by MedPath