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Knee Joint Distraction in comparison with High Tibial Osteotomy in treatment of knee osteoarthritis.

Recruiting
Conditions
Osteoarthritis, Knee
Registration Number
NL-OMON25422
Lead Sponsor
niversity Medical Center Utrecht (UMCU)
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
69
Inclusion Criteria

1. Patients with medial or lateral tibio-femoral compartmental OA considered for HTO according to regular clinical practice;

2. Age < 65 years;

Exclusion Criteria

1. Mechanic axis-deviation (varus-valgus) of less than 10 degrees;

2. Psychological inabilities or difficult to instruct;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Cartilage changes determined by decrease in denuded bone areas using quantitative MRI analyses.<br>
Secondary Outcome Measures
NameTimeMethod
1. Cartilage changes determined by X-rays, additional quantitative MRI parameters and biomarker analyses;<br /><br>2. Clinical effectiveness determined by KOOS questionnaire;<br /><br>3. Pain evaluated with VAS score;<br /><br>4. Indication of cost-effectiveness.
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