NL-OMON39144已完成3 期
Joint distraction in treatment of knee osteoarthritis: a comparison with a presently applied surgical alternative: total knee prosthesis - Knee joint distraction compared to total knee prosthesis
niversitair Medisch Centrum Utrecht0 个研究点目标入组 60 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Patients considered for TKP according to regular clinical practice
- •Age < 65 years
- •Radiological joint damage: Kellgren & Lawrence score 2 or higher
- •Intact knee ligaments
- •Normal range-of-motion (min. of 120° flexion; max flexion limitation of 15°)
- •Normal stability
- •Body Mass Index < 35
排除标准
- •Psychological inabilities or difficult to instruct
- •Not able to undergo MRI examination according to standard checklists
- •Inflammatory or rheumatoid arthritis present or in history
- •Post traumatic fibrosis due to fracture of the tibial plateau
- •Bone-to-bone contact in the joint (absence of any joint space on X-ray)
- •Surgical treatment of the involved knee < 6 months ago
- •An infectious susceptible prosthesis (joint replacement) in situ
- •Primary patello-femoral osteoarthritis
研究者
相似试验
招募中
不适用
Joint distraction in treatment of knee osteoarthritis; long-term radiographic evaluation of structural joint changesknee osteoarthritisNL-OMON45795niversitair Medisch Centrum Utrecht26
招募中
不适用
Knee Joint Distraction in comparison with Total Knee Prosthesis in treatment of knee osteoarthritis.NL-OMON26791niversital Medical Center Utrecht60
招募中
不适用
Knee Joint Distraction in comparison with High Tibial Osteotomy in treatment of knee osteoarthritis.Osteoarthritis, KneeNL-OMON25422niversity Medical Center Utrecht (UMCU)69
已完成
不适用
Joint distraction in the treatment of knee osteoarthritis; long-term efficacy (pilot)osteoarthritisjoint destruction10023213NL-OMON38528niversitair Medisch Centrum Utrecht6
已完成
不适用
Joint distraction in the treatment of knee osteoarthritis: efficacy and underlying mechanisms.Osteoarthritis of the knee is a progressing degenerative joint disorder, characterised by joint pain and limitation of movement, leading to disability. Tissue changes comprise damage of joint cartilage, synovial inflammation and changes in subchondral bone, such as subchondral sclerosis and osteophyte formation (bony outgrowths).NL-OMON20489niversity Medical Center Utrecht,Rheumatology & Clin. Immunology and Orthopaedics3